Refining the type A hypothesis: emergence of the hostility complex.
Refining the type A hypothesis: emergence of the hostility complex.
复制标题
完善 A 型假设：敌对情结的出现。
DOI：
10.1016/0002-9149(87)90680-1
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
WilliamsJr,RB
中科院分区：
文献类型：
--
作者：
WilliamsJr,RB
最近的负面研究结果对A型假设的稳健性提出了质疑。越来越多的证据表明，并非全球A型行为模式的所有方面都是致病性的，而只有那些与敌意和愤怒有关的方面。在具有高水平敌意和愤怒的人中，导致冠心病风险增加的生物学机制似乎涉及对行为挑战的心血管和神经内分泌反应增加，并且可能涉及交感神经系统效应的副交感神经拮抗作用不足。未来的研究应该集中在进一步完善我们的理解敌意复杂及其病理生理机制。
Recent negative research findings have raised questions regarding the robustness of the Type A hypothesis. A growing body of evidence suggests that not all aspects of the global Type A behavior pattern are pathogenic, but only those concerned with hostility and anger. Biologic mechanisms responsible for increased risk of coronary disease in persons with high levels of hostility and anger appear to involve increased cardiovascular and neuroendocrine responses to behavioral challenge, and, possibly, inadequate parasympathetic antagonism of sympathetic nervous system effects. Future research should concentrate on further refining our understanding of the hostility complex and its pathophysiologic mechanisms.