Sedation and its psychological effects following intensive care.
Sedation and its psychological effects following intensive care.
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DOI：
10.12968/bjon.2014.23.14.800
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发表时间：
2014-07-01
期刊：
影响因子：
--
通讯作者：
Garside, Joanne
中科院分区：
文献类型：
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作者：
Croxall, Clare;Tyas, Moira;Garside, Joanne
严重的心理影响，包括创伤后应激障碍（PTSD），与重症监护病房（ICU）中接受镇静的患者有关。然而，目前尚不清楚镇静是否以及如何与 ICU 后的心理结果相关。本文献综述探讨了镇静、镇静深度和心理障碍之间的关系。对现有文献的关键术语进行了系统回顾，包括同行评审的初步研究和随机对照试验（RCT）。为了确保 2006 年之前的主题相关性，非英语和儿科研究被排除在外。研究结果强调，镇静水平的降低并不会显着降低 PTSD 的结果，但 ICU 住院时间和机械通气 (MV) 时间的缩短均与镇静程度减轻有关。建议进一步研究 ICU 后与镇静水平和心理困扰相关的更具体的事实和妄想记忆。
Significant psychological impacts, including post-traumatic stress disorder (PTSD), have been associated with patients under sedation in intensive care units (ICUs). However, it remains unknown if and how sedation is related to post-ICU psychological outcomes. This literature review explores the relationships between sedation, the depth of sedation and psychological disorders. A review of existing literature was undertaken systematically with key terms and included peer-reviewed primary research and randomised controlled trials (RCTs). To ensure subject relevance pre-2006, non-English and paediatric-based research was excluded. Findings highlighted that reduced sedation levels did not significantly reduce the outcome of PTSD, yet reduced ICU length of stay and length of mechanical ventilation (MV) were both associated with lighter sedation. Further research is recommended into more specific factual and delusional memories post ICU in relation to the level of sedation and to psychological distress.