Vision following extended congenital blindness
Vision following extended congenital blindness
复制标题
DOI：
10.1111/j.1467-9280.2006.01827.x
复制
发表时间：
2006-12-01
影响因子：
8.2
通讯作者：
Sinha, Pawan
中科院分区：
文献类型：
--
作者：
Ostrovsky, Yuri;Andalman, Aaron;Sinha, Pawan
动物研究表明，早期视觉剥夺可导致永久性功能性失明。然而，关于这个问题的人类数据很少。如果有足够的时间恢复，一个人在先天性失明几年后能获得视觉技能吗？在印度，我们最近有一个不寻常的机会与一个人合作，他的案例历史揭示了这个问题。S.R. D他出生时是盲人，一直到12岁。然后，她接受了手术，以消除密集的先天性白内障。我们在手术后20年评估了她在广泛的视觉任务电池上的表现。我们发现，尽管S.R.D.的敏锐度受到影响，她精通中级和高级视觉任务。这些结果表明，人类的大脑在儿童后期仍然保持着令人印象深刻的视觉学习能力。他们的影响，目前的概念，皮质可塑性，并提供了一个论点，治疗先天性失明，甚至在年龄较大的儿童。
Animal studies suggest that early visual deprivation can cause permanent functional blindness. However, few human data on this issue exist. Given enough time for recovery, can a person gain visual skills after several years of congenital blindness? In India, we recently had an unusual opportunity to work with an individual whose case history sheds light on this question. S.R.D. was born blind, and remained so until age 12. She then underwent surgery for the removal of dense congenital cataracts. We evaluated her performance on an extensive battery of visual tasks 20 years after surgery. We found that although S.R.D.'s acuity is compromised, she is proficient on mid- and high-level visual tasks. These results suggest that the human brain retains an impressive capacity for visual learning well into late childhood. They have implications for current conceptions of cortical plasticity and provide an argument for treating congenital blindness even in older children.