Potassium permeability and volume control in isolated rat hepatocytes.

Potassium permeability and volume control in isolated rat hepatocytes.
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离体大鼠肝细胞的钾渗透性和体积控制。

DOI:
10.1016/0005-2736(83)90014-7
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发表时间:
1983
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
T. Bakker
T. Bakker
中科院分区:
--
文献类型:
--
作者:
T. Bakker

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(1)在离体大鼠肝细胞体积调节反应的发生进行了研究。低渗休克后,细胞能够在15分钟内收缩回其正常体积。相反,高渗休克后,细胞保持其收缩体积至少15分钟。(1980)J.Biol.Chem.255,5236-5243)。它在这里示出,这种效果是由于细胞肿胀继发于丙氨酸积累,而不是Na+-丙氨酸cotransport本身。
(1) The occurrence of volume-regulatory responses in isolated rat hepatocytes was investigated. After hypotonic shock, cells were able to shrink back to their normal volume within 15 min. By contrast, after hypertonic shock cells kept their shrunken volume for at least 15 min. (2) Na+-alanine cotransport increases K+permeability in rat hepatocytes (Kristensen, L.Ø. (1980) J. Biol. Chem. 255, 5236–5243). It is shown here that this effect is due to cell swelling secondary to alanine accumulation rather than to the Na+-alanine cotransport itself.
DOI: 10.1016/0005-2736(80)90446-0
发表时间: 1980-01-01
期刊: BIOCHIMICA ET BIOPHYSICA ACTA
影响因子: --
作者:
GECK, P;PIETRZYK, C;HEINZ, E
通讯作者: HEINZ, E