Expeditious Entry to the Chamigrane Endoperoxide Family of Natural Products
Expeditious Entry to the Chamigrane Endoperoxide Family of Natural Products
复制标题
快速进入天然产物 Chamigrane Endoperides 家族
DOI：
10.1021/ol503603t
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发表时间：
2015-02-06
期刊：
影响因子：
5.2
通讯作者：
Wu, Yikang
中科院分区：
文献类型：
--
作者：
Chen, Hui-Jun;Wu, Yikang
最近报道的过氧chamigrane家族的天然产物的几个成员通过一个新的facial-selective环氧化的spiroundecadiene，一个容易的环氧化物重排，和Co（II）-介导的硅烷基过氧化作为关键步骤的双立体选择性路线合成。适应的非对映选择性路线的对映选择性之一也说明了。
Several members of the recently reported peroxy chamigrane family of natural products were synthesized via a distereoselective route with a novel facial-selective epoxidation of a spiroundecadiene, a facile epoxide rearrangement, and a Co(II)-mediated silylperoxidation as the key steps. Adaptation of the diastereoselective route to an enantioselective one is also illustrated.