The R3 component of the blink reflex: Normative data and application in spinal lesions
The R3 component of the blink reflex: Normative data and application in spinal lesions
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DOI：
10.1016/0924-980x(96)95684-2
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发表时间：
1996-08-01
期刊：
影响因子：
--
通讯作者：
Hopf, HC
中科院分区：
文献类型：
--
作者：
Ellrich, J;Hopf, HC
眨眼反射（BR）的R3分量（R3）在鉴别延髓和颈脊髓水平病变方面的临床价值尚不清楚。在50名健康志愿者（25名女性，25名男性，年龄在20-75岁之间）中，可再现的单侧和对侧R3反应显示平均发病潜伏期为84毫秒，持续时间为32毫秒，左右差异几乎为3毫秒。潜伏期随年龄增长而增加。11例颈脊髓（C1-C6节段）病变患者的R3潜伏期正常。然而，在4例脑干病理患者中，R3异常，表现出与R2成分相同的变化。我们的研究结果表明，R3的反射不下行到颈脊髓，但在脑干内可能与R2成分具有相同的连接。
The clinical value of the R3 component (R3) of the blink reflex (BR) for differentiating between lesions at the medulla oblongata and cervical spinal cord level is still unclear. In 50 healthy volunteers (25 women, 25 men, aged 20-75 years) reproducible ipsi- and contralateral R3 responses could be evoked showing a mean onset latency of 84 ms, a duration of 32 ms and a side-to-side difference of almost 3 ms. The latency increased with age. Eleven patients with lesions of the cervical spinal cord (segments C1-C6) showed normal R3 latencies. In 4 patients with pathology of the brain-stem, however, R3 was abnormal, showing identical changes as observed with the R2 component. Our results suggest that the reflex are of R3 does not descend to the cervical spinal cord but within the brain-stem possibly takes the same connections as the R2 component.