Cancer Screening Among Older Adults: a Geriatrician's Perspective on Breast, Cervical, Colon, Prostate, and Lung Cancer Screening.
Cancer Screening Among Older Adults: a Geriatrician's Perspective on Breast, Cervical, Colon, Prostate, and Lung Cancer Screening.
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DOI：
10.1007/s11912-020-00968-x
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发表时间：
2020-08-15
影响因子：
4.7
通讯作者：
Walter LC
中科院分区：
文献类型：
--
作者：
Kotwal AA;Walter LC
我们总结的好处，危害和工具的证据，以协助在老年人中进行乳腺癌，前列腺癌，结肠癌，肺癌和宫颈癌筛查的个性化决策。老年人癌症筛查的益处尚不清楚，因为大多数随机对照试验中纳入的年龄>75岁的成年人很少。间接证据表明，在年轻人（<70岁）中看到的筛查益处可以外推到估计预期寿命至少为10年的老年人。然而，老年人，特别是那些预期寿命有限的人，可能会增加经历筛查危害的风险，包括临床上不重要疾病的过度诊断，诊断程序的并发症以及假阳性检测结果后的痛苦。我们提供了一个框架，以整合关键因素，如健康状况，特定测试的风险和益处，以及患者的偏好，以指导临床医生在老年人癌症筛查决策。
We summarize the evidence of benefits, harms, and tools to assist in individualized-decisions among older adults in screening for breast, prostate, colon, lung, and cervical cancer. The benefits of cancer screening in older adults remain unclear due to minimal inclusion of adults >75 years old in most randomized controlled trials. Indirect evidence suggests that the benefits of screening seen in younger adults (<70 years old) can be extrapolated to older adults when they have an estimated life expectancy of at least 10 years. However, older adults, especially those with limited life expectancy, may be at increased risk for experiencing harms of screening, including overdiagnosis of clinically unimportant diseases, complications from diagnostic procedures, and distress after false positive test results. We provide a framework to integrate key factors such as health status, risks and benefits of specific tests, and patient preferences to guide clinicians in cancer screening decisions in older adults.
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影响因子：
45.3
作者：
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通讯作者：
D'Amico, Anthony V.
影响因子：
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影响因子：
120.7
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通讯作者：
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