QuickTree: building huge Neighbour-Joining trees of protein sequences

QuickTree: building huge Neighbour-Joining trees of protein sequences
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DOI:
10.1093/bioinformatics/18.11.1546
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发表时间:
2002-11-01
期刊:
影响因子:
5.8
通讯作者:
Durbin, R
Durbin, R
中科院分区:
生物学3区
文献类型:
--
作者:
Howe, K;Bateman, A;Durbin, R

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我们已经编写了一个流行的邻居连接树构建算法的快速实现。QuickTree允许重建非常大的蛋白质家族(包括最大的Pfam比对,包含27000个HIV GP120糖蛋白序列)的同源性,这是使用其他流行方法不可行的。
We have written a fast implementation of the popular Neighbor-Joining tree building algorithm. QuickTree allows the reconstruction of phylogenies for very large protein families (including the largest Pfam alignment containing 27000 HIV GP120 glycoprotein sequences) that would be infeasible using other popular methods.