The impedivity of freshly excised human breast tissue
The impedivity of freshly excised human breast tissue
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DOI：
10.1088/0967-3334/19/1/006
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发表时间：
1998-02-01
影响因子：
3.2
通讯作者：
Jossinet, J
中科院分区：
文献类型：
--
作者：
Jossinet, J
一组120阻抗谱收集在乳腺组织切除后立即从64例患者接受乳房手术。测量在12个离散频率下进行，从1 MHz到488 Hz减半。将光谱分为正常组织、乳腺、结缔组织和脂肪组织三组，病理组织、乳腺病、纤维腺瘤和癌三组。在每个测量频率下，系统地进行了阻抗和导纳分量的组间多重比较。由实验数据计算了低频极限电阻率、分数功率和特征频率。除乳腺病外，未观察到阻抗和导纳与患者年龄之间的显著相关性。正常组织与良性病变（乳腺、乳腺病和纤维腺瘤）之间无显著性差异，而癌组与其他各组之间的差异主要表现在低频限电阻率、分数功率和125kHz以上的相位角。这些结果表明，阻抗谱是适当的检测乳腺癌。
A set of 120 impedivity spectra was collected in breast tissue immediately after excision from 64 patients undergoing breast surgery. The measurements were made at 12 discrete frequencies halving from 1 MHz to 488 Hz. The spectra were sorted into three groups of normal tissue, mammary gland, connective tissue and adipose tissue, and three groups of pathological tissue, mastopathy, fibroadenoma and carcinoma. Intergroup multiple comparisons of the components of impedivity and admittivity were systematically carried out at every measurement frequency. The low-frequency-limit resistivity, the fractional power and characteristic frequencies were calculated from the experimental data. No significant correlation between impedivity and admittivity and patient's age was observed, except for mastopathy. No significant difference between groups of normal tissue and benign pathology (mammary gland, mastopathy and fibroadenoma) was found. The group of carcinoma differed from all the other groups principally by the low-frequency-limit resistivity, the fractional power and the phase angle at frequency above 125 kHz. These results indicate that impedance spectroscopy is appropriate for the detection of breast cancer.