Syntheses, structures, and reactivities of borylcopper and -zinc compounds:: 1,4-silaboration of an α,β-unsaturated ketone to form a γ-siloxyallylborane
Syntheses, structures, and reactivities of borylcopper and -zinc compounds:: 1,4-silaboration of an α,β-unsaturated ketone to form a γ-siloxyallylborane
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DOI：
10.1002/anie.200801728
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发表时间：
2008-01-01
影响因子：
16.6
通讯作者：
Nozaki, Kyoko
中科院分区：
文献类型：
--
作者：
Kajiwara, Takashi;Terabayashi, Tomomi;Nozaki, Kyoko
碳负离子是有机合成化学中最重要的试剂之一。[1]由于高度极化的碳-金属键（Cd-Md+），它们充当碳亲核试剂，形成碳-碳键。碳负离子物质中极性碳-金属键的性质取决于金属对应物，例如锂、镁、铜和锌。前两种有机金属化合物直接攻击a、b-不饱和酮的羰基，而后两种[2]通过1、4-加成（共轭加成）进行反应。 [3]
Carbanions are one of the most important reagents in synthetic organic chemistry.[1] They act as a carbon nucleophile to form a carbon–carbon bond as a consequence of the highly polarized carbon–metal bonds (CdÀÀMd+). The properties of polar carbon–metal bonds in a carbanionic species depend on the metallic counterpart, such as lithium, magnesium, copper, and zinc. The first two organometallic compounds directly attack the carbonyl group of a, b-unsaturated ketones, whereas the latter two [2] react by 1, 4-addition (conjugate addition).[3]