Disuse Osteoporosis: Current Status and Problems

Disuse Osteoporosis: Current Status and Problems
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废用性骨质疏松症:现状和问题

DOI:
10.1007/978-3-642-70709-4_15
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发表时间:
1986
影响因子:
2.8
通讯作者:
H. Uhthoff
H. Uhthoff
中科院分区:
地球科学2区
文献类型:
--
作者:
Z. Jaworski;H. Uhthoff

文献摘要

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废用性骨质疏松症清楚地表明机械因素对骨结构的影响。机械负荷的突然撤回,即负重和对抗重力的体力消耗,会引发快速骨质流失(Whedon,1960;Whedon 等,1948),然而,即使在持续固定期间,骨质流失也会减轻(Minaire 等,1974;Uhthoff 和 Jaworski,1978;Whedon,1960)。这种现象表明需要调整骨量以减少机械需求。
Disuse osteoporosis clearly demonstrates the effect of mechanical factors on bone structure. Sudden withdrawal of mechanical loading, ie, of weight bearing and physical exertion against gravity, initiates a rapid bone loss (Whedon, 1960; Whedon et al, 1948) that will abate, however, even during continued immobilization (Minaire et al, 1974; Uhthoff and Jaworski, 1978; Whedon, 1960). This phenomenon suggests an adjustment of bone mass to reduced mechanical demands.