Contractile Properties of Vaginal Tissue
Contractile Properties of Vaginal Tissue
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阴道组织的收缩特性
DOI：
10.1115/1.4046712
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
De Vita, Raffaella
中科院分区：
文献类型：
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作者：
Huntington, Alyssa;Donaldson, Kandace;De Vita, Raffaella
阴道是女性生殖系统的重要器官，在生物力学领域研究较少。近年来，人们对阴道的力学性能进行了一些研究，但主要集中在被动力学性能的表征上。由于阴道收缩在性功能、分娩以及盆底疾病的发展和治疗中起着核心作用，因此也必须量化阴道的主动机械特性。本文综述和总结了已发表的关于阴道活性特性的实验研究，包括由解剖区域和取向、神经通路、生活事件(如妊娠和更年期)、盆底疾病(如脱垂)和外科网片治疗所决定的特性的差异。提出了相互矛盾的实验结果，说明有必要对阴道的活性特性进行进一步研究。然而，关于外科网片对阴道收缩的负面影响，目前已有共识。这项审查还确定了知识差距和未来的研究机会，从而为这一新兴生物力学领域的新手和有经验的研究人员奠定了坚实的基础，并鼓励在妇女的性健康和生殖健康研究方面开展更多活动。
The vagina is an important organ of the female reproductive system that has been largely understudied in the field of biomechanics. In recent years, some research has been conducted to evaluate the mechanical properties of the vagina, but much has focused on characterizing the passive mechanical properties. Because vaginal contractions play a central role in sexual function, childbirth, and development and treatment of pelvic floor disorders, the active mechanical properties of the vagina must be also quantified. This review surveys and summarizes published experimental studies on the active properties of the vagina including the differences in such properties determined by anatomic regions and orientations, neural pathways, life events such as pregnancy and menopause, pelvic floor disorders such as prolapse, and surgical mesh treatment. Conflicting experimental findings are presented, illustrating the need for further research on the active properties of the vagina. However, consensus currently exists regarding the negative impact of surgical mesh on vaginal contractility. This review also identifies knowledge gaps and future research opportunities, thus proving a firm foundation for novice and experienced researchers in this emerging area of biomechanics and encouraging more activity on women's sexual and reproductive health research.