Changes in Strength, Sensation, and Prehension in Acute Cervical Spinal Cord Injury
Changes in Strength, Sensation, and Prehension in Acute Cervical Spinal Cord Injury
复制标题
急性颈脊髓损伤时力量、感觉和预知力的变化
DOI：
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发表时间：
2015
影响因子：
4.2
通讯作者：
M. Bolliger
中科院分区：
文献类型：
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作者：
Inge;A. Curt;A. Frotzler;R. Abel;Sukhvinder Kalsi;J. Rietman;M. Bolliger
Objective.研究力量、感觉和知觉分级重新定义评估（GRASSP）工具在颈脊髓损伤（SCI）后第一年内上肢功能变化中的内外部反应和恢复情况。法一项欧洲前瞻性、纵向、多中心研究，评估颈椎SCI后1、3、6和12个月的GRASSP。根据脊髓损伤神经学分类国际标准（ISNCSCI），将GRASSP的子测试与上肢运动（UEMS）和轻触评分（LT）、脊髓独立性自我护理子评分（SCIM-SS）以及临床相关性的临床医生评定结局指标（CROM）进行比较。分析GRASSP反应性和随时间推移的恢复率数据。结果74名参与者参加了这项研究。在所有检查时间点之间，GRASSP子测试证明具有响应性（强度的标准化响应平均值[SRM]范围为0.79 - 1.48，伸展的范围为0.50 - 1.03，感觉的范围为0.14 - 0.64）。相比之下，UEMS和LT的反应性较低（SRM UEMS范围为0.69至1.29，SRM LT范围为0.30至-0.13）。所有GRASSP子测验均显示在每个时间点与UEMS、LT和SCIM-SS具有显著的中度至极好的相关性，GRASSP子测验的变化与CROM一致。1 ~ 3个月时GRASSP功能恢复最快。结论GRASSP显示出良好的反应性，检测到与颈椎脊髓损伤严重程度相关的强度和伸展度的明显变化。它检测到与ISNCSCI和SCIM-SS评估互补的临床显著变化。
Objective. To investigate the internal and external responsiveness and recovery profiles of the Graded Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP) instrument in revealing changes in upper limb function within the first year following cervical spinal cord injury (SCI). Method. A European prospective, longitudinal, multicenter study assessing the GRASSP at 1, 3, 6, and 12 months after cervical SCI. Subtests of GRASSP were compared to the upper extremity motor (UEMS) and light touch scores (LT) according to the International Standards of Neurological Classification of Spinal Cord Injury (ISNCSCI), the Spinal Cord Independence Measure self-care subscore (SCIM-SS), as well as a clinician-rated outcome measure (CROM) of clinical relevance. Data were analyzed for GRASSP responsiveness and recovery rate over time. Results. Seventy-four participants entered the study. GRASSP subtests proved responsive (standardized response mean [SRM] ranged from 0.79 to 1.48 for strength, 0.50 to 1.03 for prehension, and 0.14 to 0.64 for sensation) between all examination time points. In comparison, UEMS and LT showed lower responsiveness (SRM UEMS ranged from 0.69 to 1.29 and SRM LT ranged from 0.30 to −0.13). All GRASSP subtests revealed significant, moderate-to-excellent correlations with UEMS, LT, and SCIM-SS at each time point, and changes in GRASSP subtests were in accordance with the CROM. GRASSP prehension and motor recovery was largest between 1 and 3 months. Conclusion. The GRASSP showed excellent responsiveness, detecting distinct changes in strength and prehension relating to the severity of cervical SCI. It detected clinically significant changes complimentary to the ISNCSCI and SCIM-SS assessments.
DOI：
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发表时间：
2001-02
期刊：
The Journal of rheumatology
影响因子：
--
作者：
D. Beaton;C. Bombardier;J. Katz;J. Wright;George A. Wells;M. Boers;V. Strand;B. Shea
通讯作者：
D. Beaton;C. Bombardier;J. Katz;J. Wright;George A. Wells;M. Boers;V. Strand;B. Shea