Endurance neuromuscular electrical stimulation training improves skeletal muscle oxidative capacity in individuals with motor-complete spinal cord injury.
Endurance neuromuscular electrical stimulation training improves skeletal muscle oxidative capacity in individuals with motor-complete spinal cord injury.
复制标题
DOI：
10.1002/mus.25393
复制
发表时间：
2017-05
期刊：
影响因子：
3.4
通讯作者：
McCully KK
中科院分区：
文献类型：
--
作者：
Erickson ML;Ryan TE;Backus D;McCully KK
脊髓损伤(SCI)导致骨骼肌萎缩，肌内脂肪增加，骨骼肌氧化能力降低。神经肌肉电刺激(NMES)引发的耐力训练可能逆转这些变化，并导致肌肉代谢健康的改善。14名完全性脊髓损伤患者进行了为期16周的家庭耐力NMES膝关节伸肌训练。在训练前和训练后评估骨骼肌氧化能力、肌肉成分、血液代谢和血脂谱。在整个训练期间，宫缩次数有所增加。骨骼肌氧化能力平均提高119%，−为14%~387%(P=0.019)。在肌肉成分、血液代谢和血脂方面没有变化。耐力训练提高了骨骼肌氧化能力，而膝关节伸肌耐力训练不改变血液代谢和血脂谱。
Spinal cord injury (SCI) results in skeletal muscle atrophy, increases in intramuscular fat, and reductions in skeletal muscle oxidative capacity. Endurance training elicited with neuromuscular electrical stimulation (NMES) may reverse these changes and lead to improvement in muscle metabolic health. Fourteen participants with complete SCI performed 16 weeks of home-based endurance NMES training of knee extensors muscles. Skeletal muscle oxidative capacity, muscle composition, and blood metabolic and lipid profiles were assessed pre- and post-training. There was an increase in number of contractions performed throughout the duration of training. The average improvement in skeletal muscle oxidative capacity was 119%, ranging from −14% to 387% (P = 0.019). There were no changes in muscle composition or blood metabolic and lipid profiles. Endurance training improved skeletal muscle oxidative capacity, however endurance NMES of knee extensor muscles did not change blood metabolic and lipid profiles.