The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.
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David Gene功能分类工具：一种以生物模块为中心的新型算法，可在功能上分析大基因列表。
DOI：
10.1186/gb-2007-8-9-r183
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发表时间：
2007
期刊：
影响因子：
12.3
通讯作者：
Lempicki, Richard A
中科院分区：
文献类型：
--
作者：
Huang, Da Wei;Sherman, Brad T;Tan, Qina;Collins, Jack R;Alvord, W Gregory;Roayaei, Jean;Stephens, Robert;Baseler, Michael W;Lane, H Clifford;Lempicki, Richard A
大卫基因功能分类工具使用一种新的模糊聚类算法将基因或相关生物学术语的列表浓缩成相关基因或生物学的有组织类别，称为生物模块。大卫基因功能分类工具使用一种新的聚集算法将一系列基因或相关生物学术语浓缩成相关基因或生物学的有组织类别，称为生物模块。这种组织是通过挖掘在多个功能注释源中发现的复杂生物共现来完成的。它是一种强大的方法，将功能相关的基因和术语分组为可管理数量的生物模块，以便在网络环境中有效地解释基因列表。
The DAVID gene functional classification tool uses a novel fuzzy clustering algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.