THE TUBERCULIN TEST
THE TUBERCULIN TEST
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DOI：
10.1016/0378-1135(94)90050-7
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发表时间：
1994-05-01
影响因子：
3.3
通讯作者：
QUINN, PJ
中科院分区：
文献类型：
--
作者：
MONAGHAN, ML;DOHERTY, ML;QUINN, PJ
目前普遍使用的结核菌素试验依赖于对皮内注射结核菌素的反应，并在注射后72小时评估注射部位的肿胀。结核菌素试验的敏感性估计为68-95%，而特异性估计为96- 99%。试验的敏感性受结核菌素的效力和剂量、感染后间隔、脱敏、故意干扰、产后免疫抑制和观察者变化的影响。特异性受暴露于M的致敏作用的影响。avium，M.副结核病和环境分枝杆菌以及皮肤结核病。
Tuberculin tests in general use today rely on the response to intradermaI injections of tuberculin with assessment of the injection site for swelling at 72 hours post injection. Estimates of the sensitivity of tuberculin tests range from 68-95% while specificity is estimated to be 96-99%. The sensitivity of the test is affected by the potency and dose of tuberculin administered, the interval post-infection, desensitisation, deliberate interference, post-partum immunosuppression and observer variation. Specificity is influenced by sensitisation as a result of exposure to M. avium, M. paratuberculosis and environmental mycobaeteria and by skin tuberculosis.