Demographic Features of Japanese Patients with Sporadic Inclusion Body Myositis: A Single-center Referral Experience
Demographic Features of Japanese Patients with Sporadic Inclusion Body Myositis: A Single-center Referral Experience
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DOI：
10.2169/internalmedicine.52.8910
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发表时间：
2013-01-01
影响因子：
1.2
通讯作者：
Sobue, Gen
中科院分区：
文献类型：
--
作者：
Nakanishi, Hirotaka;Koike, Haruki;Sobue, Gen
目的日本人群中散发性包涵体肌炎（sIBM）的发病率呈上升趋势，一些研究者认为种族和遗传背景可能影响该病的临床特征。本研究的目的是澄清日本sIBM.Methods患者的人口统计学特征，我们回顾性评价了连续患者的人口统计学特征，这些患者在1995年至2011年期间被转诊到我们的机构进行诊断性肌肉活检，随后被诊断为sIBM.Results，73例患者，包括54名男性和19名女性，在研究期间接受了sIBM的诊断。根据诊断日期将患者分为两组（2002年之前和2002年之后）。每年诊断为sIBM的患者数量从2002年之前（包括2002年）的3.6 +/- 1.6（平均值+/-SD）显著增加到2002年之后的4.9 +/- 3.1（平均值+/- SD）（p
Objective The incidence of sporadic inclusion body myositis (sIBM) in the Japanese population has increased, and some researchers have suggested that race and genetic background may influence the clinical features of the disease. The aim of this study was to clarify the demographic features of Japanese patients with sIBM.Methods We retrospectively evaluated the demographic features of consecutive patients who were referred to our institution between 1995 and 2011 for diagnostic muscle biopsies and who subsequently were diagnosed to have sIBM.Results Seventy-three patients comprising 54 men and 19 women received a diagnosis of sIBM during the study period. The patients were divided into two groups based on the date of diagnosis (before and including 2002, and after 2002). The annual number of patients who received a diagnosis of sIBM increased significantly from 3.6 +/- 1.6 (mean +/- SD) before and including 2002 to 4.9 +/- 3.1 (mean +/- SD) after 2002 (p