Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency
Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency
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DOI：
10.1359/jbmr.040609
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发表时间：
2004-11-01
影响因子：
6.2
通讯作者：
Manicourt, DH
中科院分区：
文献类型：
--
作者：
Behets, C;Williams, JM;Manicourt, DH
由于SBM可能导致OA中的软骨破坏，因此通过横断膝关节前交叉韧带并用CT或安慰剂治疗来诱导犬实验性OA。CT显着减少SBM和软骨病变。本研究支持使用CT治疗犬实验性OA。
Because SBM may contribute to cartilage breakdown in OA, experimental OA was induced in dogs by transecting the anterior cruciate ligament of the knee and treating with either CT or a placebo. CT significantly reduced both SBM and cartilage lesions. This study supports the use of CT in the treatment of canine experimental OA.