IDENTIFICATION AND 3-D QUANTIFICATION OF ATHEROSCLEROSIS USING MAGNETIC-RESONANCE IMAGING
IDENTIFICATION AND 3-D QUANTIFICATION OF ATHEROSCLEROSIS USING MAGNETIC-RESONANCE IMAGING
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DOI：
10.1016/0010-4825(88)90035-2
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发表时间：
1988-01-01
影响因子：
7.7
通讯作者：
AYERS, CR
中科院分区：
文献类型：
--
作者：
MERICKEL, MB;CARMAN, CS;AYERS, CR
动脉粥样硬化引起的心血管疾病是美国和其他发达国家的主要死亡原因。本文介绍了图像处理，模式识别和图形显示技术的发展，非侵入性量化动脉粥样硬化疾病的过程中使用磁共振成像（MRI）。我们已经证明了识别以下软组织类别的能力：（1）正常平滑肌壁，（2）脂肪斑块，（3）复杂纤维斑块和（4）钙化斑块。这项工作的目的是将功能信息（如斑块组织类型）与由血管结构的3-D显示表示的结构信息联合收割机组合成单个复合显示。这项工作的结果提供了一个“高信息含量”的显示，这将有助于诊断和分析动脉粥样硬化疾病的过程，并允许详细和定量的研究，以评估治疗的有效性（例如，饮食，运动和药物管理的变化）。
Cardiovascular disease due to atherosclerosis is a leading cause of death in the United States as well as other developed countries. This paper describes the development of image processing, pattern recognition, and graphical display techniques to non-invasively quantify the atherosclerotic disease process using magnetic resonance imaging (MRI). We have demonstrated the ability to identify the soft tissue classes of (1) normal, smooth muscle wall, (2) fatty plaque, (3) complex, fibrous plaque, and (4) calcified plaque. The objective of this work has been to combine functional information, such as plaque tissue type, with structural information, represented by 3-D display of vessel structure, into a single composite display. The results of this work provide a "high information content" display which will aid in the diagnosis and analysis of the atherosclerotic disease process, and permit detailed and quantitative studies to assess the effectiveness of therapies (e.g. changes in diet, exercise and drug administration).