Hybrid adiabatic-rectangular pulse train for effective saturation of magnetization within the whole heart at 3 T.
Hybrid adiabatic-rectangular pulse train for effective saturation of magnetization within the whole heart at 3 T.
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DOI:
10.1002/mrm.22140
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发表时间:
2009-12
影响因子:
3.3
通讯作者:
McGorty, KellyAnne
中科院分区:
文献类型:
--
作者:
Kim, Daniel;Oesingmann, Niels;McGorty, KellyAnne
关键词:
Uniform T1-weighting is a major challenge for first-pass cardiac perfusion MRI at 3T. Previously proposed adiabatic B1-insensitive rotation (BIR-4) pulse and standard and tailored pulse trains of three non-selective pulses have been important developments but each pulse has limitations at 3T. As an extension of the tailored pulse train, we developed a hybrid pulse train by synergistically combining two non-selective rectangular RF pulses and an adiabatic half-passage pulse, in order to achieve effective saturation of magnetization within the heart, while remaining within clinically acceptable specific absorption rate (SAR) limits. The standard pulse train, tailored pulse train, hybrid pulse train, and BIR-4 pulse train were evaluated through numerical, phantom, and in vivo experiments. Among the four saturation pulses, only the hybrid pulse train yielded residual magnetization < 2% of equilibrium magnetization in the heart, while remaining within clinically acceptable SAR limits for multi-slice first-pass cardiac perfusion MRI at 3T.
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