On matching compliance between canine carotid arteries and polyurethane grafts.
On matching compliance between canine carotid arteries and polyurethane grafts.
复制标题
关于犬颈动脉和聚氨酯移植物之间的匹配顺应性。
DOI：
10.1111/j.1525-1594.1997.tb00485.x
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发表时间：
1997
影响因子：
2.4
通讯作者：
Kambic,H
中科院分区：
文献类型：
--
作者：
Hsu,S;Kambic,H
宿主动脉和植入的移植物之间的顺应性不匹配被认为是小直径移植物失败的一个促成因素。本研究对犬颈动脉和两种聚氨酯人工血管的静态顺应性和动态顺应性进行了体外和体内的测量。基于这些顺应性值，计算周向模量（Eθ）和纵向模量（Ez）。结果表明，移植物在较宽的压力范围内具有恒定的弹性模量，而颈动脉的弹性模量随压力的增加而显著增加（动态E θ从0.20 ~ 1.32MPa）。聚氨酯移植物几乎是各向同性的，在每个方向上的模量几乎相同，而颈动脉是各向异性的（Eθ Ez=2-3）。动态模量通常高于静态值，并且对于动脉尤其明显。由于这些不同的固有特性，合成移植物的顺应性可能仅在周向方向和小的压力范围内匹配宿主动脉的顺应性。因此，对于完全顺应性匹配给出了规定的限制。结果提供了一个合理的识别程度的符合性匹配。这些努力可能会导致更好的设计血管移植。
Compliance mismatch between a host artery and an implanted graft has been suggested as a contributing factor to a small diameter graft failure. In this study, static compliance and dynamic compliance were defined and measured in vitro and in vivo for canine carotid arteries and 2 types of polyurethane grafts. Based on these compliance values, the circumferential modulus (Eθ) and longitudinal modulus (Ez) were calculated. It was shown that grafts have constant moduli over a wide range of pressure while the moduli of carotid arteries increase significantly with increasing pressure (dynamicEθfrom 0.20 to 1.32 MPa). Polyurethane grafts are nearly isotropic, with the modulus almost identical in each direction, while carotid arteries are anisotropic (Eθ Ez=2–3). The dynamic moduli are generally higher than static values and are especially pronounced for arteries. Due to these different inherent characteristics, the compliance of a synthetic graft may match that of the host artery only in the circumferential direction and within a small pressure range. A stated limitation is therefore given for complete compliance matching. The results provide a rationale for identifying the degree of compliance match. These efforts may lead to better designed vascular grafts.