The START App: a web-based RNAseq analysis and visualization resource
The START App: a web-based RNAseq analysis and visualization resource
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DOI：
10.1093/bioinformatics/btw624
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发表时间：
2017-02-01
期刊：
影响因子：
5.8
通讯作者：
Minnier, Jessica
中科院分区：
文献类型：
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作者：
Nelson, Jonathan W.;Sklenar, Jiri;Minnier, Jessica
使用RNA测序的转录谱分析（RNAseq）已经成为一种强大的方法，用于量化从单细胞到整个组织的各种背景下的全局基因表达模式。这种分析技术生成的大量数据在有效地可视化和解释结果方面提出了艰巨的挑战。方便直观的数据界面对于研究人员轻松上传、分析和可视化RNAseq数据至关重要。我们设计START（闪亮转录组分析资源工具）应用程序时考虑到了这些要求。该应用程序具有强大的功能和灵活性，可以驻留在本地计算机上，也可以作为基于Web的环境，使研究人员和合作者之间可以轻松共享数据。
Transcriptional profiling using RNA sequencing (RNAseq) has emerged as a powerful methodology to quantify global gene expression patterns in various contexts from single cells to whole tissues. The tremendous amount of data generated by this profiling technology presents a daunting challenge in terms of effectively visualizing and interpreting results. Convenient and intuitive data interfaces are critical for researchers to easily upload, analyze and visualize their RNAseq data. We designed the START (Shiny Transcriptome Analysis Resource Tool) App with these requirements inmind. This application has the power and flexibility to be resident on a local computer or serve as a web-based environment, enabling easy sharing of data between researchers and collaborators.