Neurological diseases in Peru: a systematic analysis of the global burden disease study
Neurological diseases in Peru: a systematic analysis of the global burden disease study
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DOI：
10.1590/0004-282x20200018
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发表时间：
2020-05-01
影响因子：
1.4
通讯作者：
ROMERO-SANCHEZ, Roberto
中科院分区：
文献类型：
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作者：
ALVA-DÍAZ, Carlos;HUERTA-ROSARIO, Andrely;ROMERO-SANCHEZ, Roberto
背景：疾病负担指标评估疾病对人群的影响。它们将死亡率和残疾纳入一个单一指标。这使得能够确定保健服务的优先事项并集中资源。目的：分析1990-2015年秘鲁神经系统疾病的负担。研究方法：一项描述性研究，使用了1990年至2015年全球疾病负担健康评估和评估研究所发布的流行病学数据。疾病负担是用伤残调整生命年（DALY）及其相应的95%不确定区间（UI）来衡量的，这些不确定区间是由损失生命年（YLL）和伤残生存年（YLD）相加得出的。结果：1990年和2015年，秘鲁的神经系统疾病负担分别为9.06%和10.65%。2015年，主要原因是偏头痛、脑血管病（CVD）、新生儿脑病（NE）和阿尔茨海默病和其他痴呆症（ADD）。与1990年相比，最后一组癌症和神经系统癌症分别增加了157%和183%的DALY。年轻人（25 ~ 44岁）和老年人（>85岁）是DALY最高的年龄组。神经系统疾病分别占全国YLL（心血管疾病为主要原因）和YLD（偏头痛为主要原因）的11.06%和10.02%。结论：1990年至2015年，疾病负担（BD）增加了1.6%。主要病因为偏头痛、心血管疾病和NE。ADD和NSC在此期间将DALY翻了一番。这些疾病是造成残疾的一个重要原因，原因之一是我国人口预期寿命的延长。应采取优先行动预防和治疗这些原因。
Background: Disease burden indicators assess the impact of disease on a population. They integrate mortality and disability in a single indicator. This allows setting priorities for health services and focusing resources. Objective: To analyze the burden of neurological diseases in Peru from 1990-2015. Methods: A descriptive study that used the epidemiological data published by the Institute for Health Metrics and Evaluation of Global Burden of Diseases from 1990 to 2015. Disease burden was measured using disability-adjusted life years (DALY) and their corresponding 95% uncertainty intervals (UIs), which results from the addition of the years of life lost (YLL) and years lived with disability (YLD). Results: The burden of neurological diseases in Peru were 9.06 and 10.65%, in 1990 and 2015, respectively. In 2015, the main causes were migraine, cerebrovascular disease (CVD), neonatal encephalopathy (NE), and Alzheimer's disease and other dementias (ADD). This last group and nervous system cancer (NSC) increased 157 and 183% of DALY compared to 1990, respectively. Young population (25 to 44 years old) and older (>85 years old) were the age groups with the highest DALY. The neurological diseases produced 11.06 and 10.02% of the national YLL (CVD as the leading cause) and YLD (migraine as the main cause), respectively.Conclusion: The burden of disease (BD) increased by 1.6% from 1990 to 2015. The main causes were migraine, CVD, and NE. ADD and NSC doubled the DALY in this period. These diseases represent a significant cause of disability attributable to the increase in the life expectancy of our population among other factors. Priority actions should be taken to prevent and treat these causes.