Pulmonary Endarterectomy Patient Selection, Technical Challenges, and Outcomes
Pulmonary Endarterectomy Patient Selection, Technical Challenges, and Outcomes
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DOI：
10.1513/annalsats.201601-014as
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发表时间：
2016-07-01
影响因子：
8.3
通讯作者：
Jenkins, David P.
中科院分区：
文献类型：
--
作者：
Madani, Michael;Mayer, Eckhard;Jenkins, David P.
在慢性血栓栓塞性肺动脉高压中，血栓栓塞不经过溶解，而是变得高度组织化和纤维化，导致肺血管树的部分阻塞。随之而来的是进行性肺动脉高压，伴随大量相关的发病率和死亡率。尽管某些类型的肺动脉高压的医学治疗取得了进展，外科肺动脉内膜切除术，也称为肺血栓动脉内膜切除术，仍然是慢性血栓栓塞性肺动脉高压患者唯一的潜在治疗选择。本文回顾了患者的选择、手术技术和肺动脉内膜切除术的结果。
In chronic thromboembolic pulmonary hypertension, thromboemboli do not undergo resolution but instead become highly organized and fibrotic, resulting in obstruction of segments of the pulmonary vascular tree. Progressive pulmonary hypertension ensues, with substantial associatedmorbidity andmortality. Despite advances in medical therapy for some types of pulmonary hypertension, surgical pulmonary endarterectomy, also referred to as pulmonary thromboendarterectomy, remains the only potentially curative option for patients with chronic thromboembolic pulmonary hypertension. This article reviews patient selection, surgical technique, and outcomes for pulmonary endarterectomy in this patient population.