Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography
Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography
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DOI：
10.1111/j.1464-410x.2008.07587.x
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发表时间：
2008-08-01
影响因子：
4.5
通讯作者：
Strasser, Hannes
中科院分区：
文献类型：
--
作者：
Pinggera, Germar-Michael;Mitterberger, Michael;Strasser, Hannes
目标进行调查。使用经直肠彩色多普勒超声检查（TRCDUS），在患有下尿路症状（LUTS）的老年患者中，膀胱和前列腺的灌注是否减少，这在以后的生活中很常见，因为实验数据表明慢性缺血在 LUTS 的发展中起着关键作用。 患者、受试者和方法在 32 名老年患者中 1（12 名女性，平均年龄 82.3 岁，第 1 组；20 名男性， 79.4 岁，第 2 组）使用 TRCDUS 测量膀胱颈（女性）和膀胱颈和前列腺（男性）的灌注和电阻指数（I 和颜色像素密度（Cl 测定，通过 TRUS 装置和特殊软件评估）。为了评估年龄相关效应，两个对照组分别由 10 名年轻健康女性（平均年龄 42.3 岁。第 3 组）和 10 名年龄匹配的健康男性（平均年龄 41.5 岁，第 3 组）组成。 4）也被纳入。结果无论性别如何，老年 LUTS 患者的膀胱灌注明显低于年轻受试者。第 1 组膀胱颈的平均 (SD) RI 为 0.88 (0.06)，第 2 组为 0.80 (0.08)，高于对照组 3 的 0.62 (0.05) 和第 4 组的 0.64 (0.09)。的 CPD 测量结果相似。每日和每晚排尿的频率与膀胱灌注呈强烈负相关。结论在老年 I 患者中，使用 TRCDUS 进行评估时，膀胱颈和前列腺的灌注减少。因此，随着年龄的增长，膀胱灌注减少可能是 LUTS 发生的原因。
OBJECTIVESTo investigate. using transrectal colour Doppler ultrasonography, (TRCDUS) whether perfusion of the bladder and prostate is reduced in elderly patients with lower urinary tract symptoms (LUTS), common in later life, as experimental data suggest that chronic ischaemia has a key role in the development of LUTS.PATIENTS, SUBJECTS AND METHODSIn 32 elderly patients with 1 (12 women, mean age 82.3 years, group 1; and 20 men, 79.4 years, group 2) perfusion of the bladder neck (in women) and of the bladder neck and prostate (in men) was measured using TRCDUS and the resistive index (I and colour pixel density (Cl determined, assessed by a TRUS unit and special software. To assess the age-related effect two control groups of 10 young healthy women (mean age 42.3 years. group 3) and 10 age-matched healthy men (mean age 41.5 years, group 4) were also enrolled.RESULTSIrrespective of gender, there was markedly lower bladder perfusion in elderly patients with LUTS than in the younger subjects. The mean (SD) RI of the bladder neck in group 1, of 0.88 (0.06), and group 2, of 0.80 (0.08), was higher than in control groups 3. of 0.62 (0.05) and group 4, of 0.64 (0.09). The results were similar for the CPD measurements. The frequency of daily and nightly micturition showed a strong negative correlation with perfusion in the urinary bladder.CONCLUSIONIn elderly patients with I there was decreased perfusion of the bladder neck and prostate when assessed using TRCDUS. Therefore, decreased perfusion in the urinary bladder might be responsible for the development of LUTS with advancing age.