T 1-mapping and dielectric properties evaluation of a 3D printable rubber-elastomeric polymer as tissue mimicking materials for MRI phantoms
T 1-mapping and dielectric properties evaluation of a 3D printable rubber-elastomeric polymer as tissue mimicking materials for MRI phantoms
复制标题
3D 打印橡胶弹性体聚合物作为 MRI 体模组织模拟材料的 T 1 映射和介电性能评估
作者：
Lotfi Talalwa;G. Natour;A. Bauer;A. Drzezga;A. Gordji;S. Beer
在这项研究中，研究了一系列新的3D打印橡胶弹性体聚合物（称为PORO-LAY材料），研究了它们作为MRI体模组织模拟材料（TSTO）的适用性。PORO-LAY材料先前已用于生物燃料电池开发、颗粒过滤和弹性组织建模。我们评估了介电常数，电导率，自旋晶格T1弛豫时间，并在3.0 T下获得了由PORO-LAY材料制成的简单和多材料复杂3D打印形状的MRI对比度。结果显示PORO-LAY材料内的T1多样性，这在不同的MR图像对比度中得到了揭示。结果支持PORO-LAY作为适当的候选材料，可用于多材料增材制造，以产生逼真的形状，例如具有可见清晰对比度的MRI体模的白色/灰质结构。最后，这项研究可以作为一个参考和指南时，使用这些材料作为组织模拟材料的不同类型的人体组织，并提供了一个有前途的机会，设计新的幻影广泛的MRI应用。
In this study, a new series of 3D printable rubber-elastomeric polymer called PORO-LAY materials have been investigated regarding their suitability to serve as tissue mimicking materials (TMMs) for MRI phantoms. PORO-LAY materials have been previously used in biofuel cell developments, particle filtrations and modeling elastic tissues. We evaluated the electrical permittivity, electrical conductivity, spin-lattice T 1-relaxation time and acquired the MRI contrast for simple and multi-material complex 3D printed shapes made of PORO-LAY materials at 3.0 T. The results showed a T 1 diversity within PORO-LAY materials, which reveals in different MR image contrasts. The outcome favors PORO-LAY as an appropriate candidate that can be used in multi-materials additive manufacturing to produce realistic shapes such as white/grey matter structures for MRI phantoms with visible clear contrast. Finally, this study could serve as a reference and guideline when using these materials as tissue mimicking materials for different types of human body tissues and provide a promising opportunity to design novel phantoms for a wide range of MRI applications.
影响因子：
3.8
作者：
D'Souza, WD;Madsen, EL;Thomadsen, BR
通讯作者：
Thomadsen, BR