Incidence of post-stroke depression symptoms and potential risk factors in adults with aphasia in a comprehensive stroke center.
Incidence of post-stroke depression symptoms and potential risk factors in adults with aphasia in a comprehensive stroke center.
复制标题
综合性卒中中心成人失语症患者卒中后抑郁症状的发生率和潜在危险因素。
DOI：
10.1080/10749357.2022.2070363
复制
发表时间：
2023
影响因子：
2.2
通讯作者：
Belagaje,SamirR
中科院分区：
文献类型：
--
作者：
Zanella,Christina;Laures-Gore,Jacqueline;Dotson,VonettaM;Belagaje,SamirR
抑郁是脑卒中后常见的后遗症，但其发病率鲜有报道。卒中后抑郁（PSD）的可能性可能与个体因素有关，包括失语症的存在，这也使PSD诊断复杂化。本研究的目的是调查成年失语症患者PSD症状的发生率，将其与无失语症的成年人PSD症状的发生率进行比较，方法采用2005年至2009年期间在一家城市三级医疗学术机构和综合性卒中中心收集的970例患者记录的数据，计算发生率比例和相对风险。2019年。专注于成年人失语症，年龄，性别，种族和失语症的严重程度所选择的变量进行Logistic回归分析，探讨潜在的危险因素，有助于发展的PSD.ResultsAdults与失语症的成年人表现出PSD症状的可能性是7.408倍，比没有失语症的成年人。控制失语症存在的逻辑回归显示失语症严重程度和卒中后抑郁症状之间存在显著关系。成人失语症的2.06倍更有可能经历中风后抑郁症状，每增加1点失语症severity.ConclusionsThese研究结果与早期的证据表明，失语症经历PSD症状的危险因素，也表明失语症的严重程度是成比例的风险。这突出了需要早期识别PSD症状的失语症患者，以便提供及时的干预措施。
IntroductionDepression may be a frequent sequela after stroke, however, its incidence has rarely been reported. The likelihood of post-stroke depression (PSD) may relate to individual factors including the presence of aphasia, which also complicates PSD diagnosis. The current study’s purpose was to investigate the incidence of PSD symptoms in adults with aphasia, compare it to the incidence of PSD symptoms in adults without aphasia, and to identify potential risk factors for developing PSD in adults with aphasia.MethodIncidence proportions and relative risk were calculated using data compiled from 970 patient records at an urban tertiary care academic institution and comprehensive stroke center throughout the year of 2019. Focusing exclusively on adults with aphasia, the selected variables of age, gender, race, and aphasia severity were used to conduct logistic regression analyses to explore potential risk factors contributing to the development of PSD.ResultsAdults with aphasia were 7.408 times more likely to exhibit PSD symptoms than adults without aphasia. Logistic regression controlling for the presence of aphasia showed a significant relationship between aphasia severity and post-stroke depression symptoms. Adults with aphasia were 2.06 times more likely to experience post-stroke depression symptoms with every 1-point increase in aphasia severity.ConclusionsThese findings align with earlier evidence identifying aphasia as a risk factor for experiencing PSD symptoms and also suggest aphasia severity is proportionate to the risk. This highlights the need for early identification of PSD symptoms in persons with aphasia in order to provide timely interventions.