Classification and quantification of neuronal fiber pathways using diffusion tensor MRI
Classification and quantification of neuronal fiber pathways using diffusion tensor MRI
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DOI：
10.1002/mrm.10415
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发表时间：
2003-04-01
影响因子：
3.3
通讯作者：
Anderson, AW
中科院分区：
文献类型：
--
作者：
Ding, ZH;Gore, JC;Anderson, AW
体内神经元纤维通路的定量表征具有重要的神经学和临床意义。利用 MR 扩散张量成像的能力来确定神经元纤维的局部方向，开发了新的算法，将体内重建的神经元纤维通路与扩散张量图像捆绑在一起，并量化纤维束的各种物理和几何特性。通过再现性测试来检查算法的可靠性。说明性结果表明，可以获得神经元组织新特性的一致物理和几何测量，这为体内纤维通路的定量研究提供了巨大的潜力。 (C) 2003 Wiley-Liss, Inc.
Quantitative characterization of neuronal fiber pathways in vivo is of significant neurological and clinical interest. Using the capability of MR diffusion tensor imaging to determine the local orientations of neuronal fibers, novel algorithms were developed to bundle neuronal fiber pathways reconstructed in vivo with diffusion tensor images and to quantify various physical and geometric properties of fiber bundles. The reliability of the algorithms was examined with reproducibility tests. Illustrative results show that consistent physical and geometric measurements of novel properties of neuronal tissue can be obtained, which offer considerable potential for the quantitative study of fiber pathways in vivo. (C) 2003 Wiley-Liss, Inc.