CORYNEBACTERIUM PSEUDOTUBERCULOSIS - NEW CAUSE OF INFECTIOUS AND EOSINOPHILIC PNEUMONIA
CORYNEBACTERIUM PSEUDOTUBERCULOSIS - NEW CAUSE OF INFECTIOUS AND EOSINOPHILIC PNEUMONIA
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DOI：
10.1016/0002-9343(79)90395-4
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发表时间：
1979-01-01
影响因子：
5.9
通讯作者：
LUTCH, JS
中科院分区：
文献类型：
--
作者：
KESLIN, MH;MCCOY, EL;LUTCH, JS
一名28岁的兽医学生出现高烧、咳嗽、外周血嗜酸性粒细胞增多和嗜酸性肺浸润性病变。假结核杆菌是从经气管抽吸物和支气管镜冲洗中分离出来的。假结核杆菌是一种引起家畜淋巴结炎的病原体，但从来没有报告过会导致人患肺炎。在先前报告的4例假性结核中，淋巴结炎是主要的临床表现。在这例患者中，出现了针对分离的假结核杆菌的特异性抗体，但没有针对其他棒状细菌。红霉素治疗后外周血嗜酸粒细胞和Ig[免疫球蛋白]E抗C。假结核抗体滴度下降，而免疫球蛋白抗体滴度继续上升。
A 28 yr old veterinary medical student experienced spiking fever, cough, peripheral blood eosinophilia and an eosinophilic pulmonary infiltrate. C. pseudotuberculosis was isolated from a transtracheal aspirate and bronchoscopy washings. C. pseudotuberculosis, a pathogen responsible for lymphadenitis in livestock, has never been reported to cause pneumonia in man. In the 4 cases of C. pseudotuberculosis previously reported, lymphadenitis was the chief clinical presentation. In this patient, specific antibodies against the isolated C. pseudotuberculosis developed but not against the other corynebacteria. With erythromycin therapy, the peripheral blood eosinophilia and Ig[immunoglobulin]E anti-C. pseudotuberculosis titer decreased but the IgG titer continued to increase.