Aging of the Chromatic Onset Visual Evoked Potential

Aging of the Chromatic Onset Visual Evoked Potential
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彩色起始视觉诱发电位的老化

DOI:
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发表时间:
2001
影响因子:
1.4
通讯作者:
and ANDREA Fuhrel
and ANDREA Fuhrel
中科院分区:
医学4区
文献类型:
--
作者:
Jonathan W. Page;and ANDREA Fuhrel

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目的。目的:研究变色性视觉诱发电位(VEP)随年龄的变化。方法:研究方法。分别对L-M通道和S−(L+M)通道进行调制,并以起始-偏置模式呈现。还测量了对以反转模式呈现的消色差光栅的响应。20名受试者接受了测试,年龄从21岁到93岁不等。结果。与生命早期观察到的变化不同,彩色起始波形的一般形状随年龄变化不大;然而,潜伏期随着年龄的增加而显著增加。波幅变化显示出一种下降的趋势,但没有统计学意义。消色差反应随年龄增长变化不大。结论。我们的结果表明,随着年龄的增长,发色的视觉诱发电位出现系统性的减慢。潜伏期变化的渐进性和缺乏戏剧性和复杂的波形变化可能允许开发用于临床环境的基于年龄的规范数据。
Purpose. To examine changes in the chromatic onset visual evoked potential (VEP) as a function of aging. Methods. VEP’s were measured in response to chromatic sinusoidal gratings (1.0 and 0.5 cpd), selectively chosen to modulate the L-M channel and S − (L+M) channel and presented in onset-offset mode. Responses to achromatic gratings presented in a reversal mode were also measured. Twenty subjects were tested, ranging in age from 21 to 93 years. Results. Unlike changes observed earlier in life, the general shape of the chromatic onset wave-form changed little with age; however, latencies increased significantly as a function of age. Amplitude changes revealed a decreasing trend that was not statistically significant. There was little change in the achromatic responses with age. Conclusions. Our results demonstrate a systematic slowing of the chromatic onset VEP with age. The gradual nature of the latency changes and the lack of dramatic and complex wave-form shape changes may allow development of age-based normative data for use in clinical settings.
DOI: 10.1093/cercor/8.4.295
发表时间: 1998-06-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
Peters, A;Morrison, JH;Hyman, BT
通讯作者: Hyman, BT
DOI: 10.1113/jphysiol.1984.sp015499
发表时间: 1984-01-01
影响因子: 5.5
作者:
DERRINGTON, AM;KRAUSKOPF, J;LENNIE, P
通讯作者: LENNIE, P
DOI: 10.1364/josaa.10.001818
发表时间: 1993-08-01
影响因子: 1.9
作者:
CROGNALE, MA;SWITKES, E;ADAMS, AJ
通讯作者: ADAMS, AJ