Comparison of Expert Adjudicated Coronary Heart Disease and Cardiovascular Disease Mortality With the National Death Index: Results From the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Comparison of Expert Adjudicated Coronary Heart Disease and Cardiovascular Disease Mortality With the National Death Index: Results From the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
复制标题
DOI：
10.1161/jaha.116.004966
复制
发表时间：
2017-05-01
影响因子：
5.4
通讯作者：
Levitan, Emily B.
中科院分区：
文献类型：
--
作者：
Olubowale, Olusola Tope;Safford, Monika M.;Levitan, Emily B.
国家死亡指数（NDI）被广泛用于检测冠心病（CHD）和心血管疾病（CVD）死亡，方法和结果-我们比较了NDI检测的CHD和CVD死亡与2003年至2013年发生在REGARDS参与者中的4010例死亡的专家裁定（中风的地理和种族差异的原因）美国黑人和白色成年人队列。NDI预测冠心病死亡率的敏感性为53.6%，特异性为90.3%，阳性预测值为54.2%，阴性预测值为90.1%。NDI衍生的CVD死亡率的敏感性为73.4%，特异性为84.5%，阳性预测值为70.6%，阴性预测值为86.2%。在NDI衍生的CHD和CVD死亡中，（比值比，每1年增加1.06和1.04）与裁定的死亡原因不一致的概率较高相关，而在REGARDS裁定的CHD和CVD死亡中，CHD或CVD病史与NDI衍生的死亡原因不一致的概率较低相关结论：NDI衍生的死亡原因的适度准确性和差异表现可能影响CHD和CVD死亡率统计。
Background-The National Death Index (NDI) is widely used to detect coronary heart disease (CHD) and cardiovascular disease (CVD) deaths, but its reliability has not been examined recently.Methods and Results-We compared CHD and CVD deaths detected by NDI with expert adjudication of 4010 deaths that occurred between 2003 and 2013 among participants in the REGARDS (REasons for Geographic And Racial Differences in Stroke) cohort of black and white adults in the United States. NDI derived CHD mortality had sensitivity 53.6%, specificity 90.3%, positive predictive value 54.2%, and negative predictive value 90.1%. NDI-derived CVD mortality had sensitivity 73.4%, specificity 84.5%, positive predictive value 70.6%, and negative predictive value 86.2%. Among NDI-derived CHD and CVD deaths, older age (odds ratios, 1.06 and 1.04 per 1-year increase) was associated with a higher probability of disagreement with the adjudicated cause of death, whereas among REGARDS adjudicated CHD and CVD deaths a history of CHD or CVD was associated with a lower probability of disagreement with the NDI-derived causes of death (odds ratios, 0.59 and 0.67, respectively).Conclusions-The modest accuracy and differential performance of NDI-derived cause of death may impact CHD and CVD mortality statistics.