Characterization of human T-cell subpopulations as defined by specific receptors for immunoglobulins.
Characterization of human T-cell subpopulations as defined by specific receptors for immunoglobulins.
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由免疫球蛋白特异性受体定义的人类 T 细胞亚群的特征。
DOI：
10.1007/978-1-4684-0922-2_2
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
Max D. Cooper
中科院分区：
文献类型：
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作者：
L. Moretta;Manlio Ferrarini;Max D. Cooper
免疫球蛋白（IG）分子的受体已在几种动物的单核“淋巴样”细胞上检测到。对相关细胞群的分析表明，单核细胞、巨噬细胞和淋巴细胞表达IG受体（Didder，1976）。淋巴细胞亚群的研究已经表明，T细胞（Lee和Paraskevas，1972; Yoshida和Andersson，1972; Soteriades-Vlachos等，1974;安德森和Grey，1974; Ferrarini等，1915 a; Winchester等，1975; Brown和Greaves，1974）、B细胞（Basten等，一九七二年; Dickler和Kunkel，1972），以及第三个亚群的非T、非B细胞，其未被完全表征，通常被称为“空细胞”（Froland和Natvig，1973; Kurnick和Grey，1975; Horwitz和加勒特，1977），可能具有免疫球蛋白受体。早期对淋巴细胞的研究主要揭示了IgG分子的受体，如果不是唯一的话，但最近已经描述了其他1g类的受体。在正常和白血病T淋巴细胞上都发现了IgM受体（Moretta et al.，1975; McConnell和Hurd，1976; Gmelig-Meyling等人，1976; Moretta等，1911 a）和B淋巴细胞（Hichler和克纳普，1977; Ferrarini等，1977），而IgE受体已在人B细胞亚群上检测到（GonzalesMolina和Spiegelberg，1977）。
Receptors for immunoglobulin (Ig) molecules have been detected on mononuclear “lymphoid” cells of several animal species. Analysis of thecellular populations involved has demonstrated that Ig receptors are expressed by monocytes, macrophages, and lymphocytes (Didder, 1976). Studies of lymphocyte subpopulations have shown that T cells (Lee and Paraskevas, 1972; Yoshida and Andersson, 1972; Soteriades-Vlachos et al, 1974; Anderson and Grey, 1974; Ferrarini et al, 1915a; Winchester et al, 1975; Brown and Greaves, 1974), B cells (Basten et al., 1972; Dickler and Kunkel, 1972), and a third subset of non-T, non-B cells, not fully characterized and often referred to as “null cells” (Froland and Natvig, 1973; Kurnick and Grey, 1975; Horwitz and Garrett, 1977), may possess receptors for immunoglobulin. Early studies on lymphocytes revealed receptors for IgG molecules mainly, if not exclusively, but receptors for other 1g classes have been described more recently. Receptors for IgM have been found on both normal and leukemic T lymphocytes (Moretta et al., 1975; McConnell and Hurd, 1976; Gmelig-Meyling et al., 1976; Moretta et al, 1911a) and B lymphocytes (Hichler and Knapp, 1977; Ferrarini et al., 1977), while receptors for IgE have been detected on a subpopulation of human B cells (GonzalesMolina and Spiegelberg, 1977).