Couples-focused behavioral interventions for prevention of HIV: systematic review of the state of evidence.
Couples-focused behavioral interventions for prevention of HIV: systematic review of the state of evidence.
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DOI：
10.1007/s10461-008-9471-4
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发表时间：
2010-02
影响因子：
4.4
通讯作者：
Operario, Don
中科院分区：
文献类型：
--
作者：
Burton, Jennifer;Darbes, Lynae A.;Operario, Don
艾滋病毒经常在有忠诚关系的伴侣中传播，因此以夫妻为中心的艾滋病毒预防干预措施是减少感染的一种潜在有前途的方式。我们对研究进行了系统回顾，测试以夫妇为中心的行为预防干预措施是否可以减少艾滋病毒传播和危险行为。我们纳入了使用随机对照试验设计、半随机对照试验和非随机对照研究的研究。我们检索了5个电子数据库，筛选了7628条记录。纳入 1,084 对夫妇的六项研究符合纳入标准，并纳入本次综述。各项研究的结果一致表明，与对照组相比，以夫妻为中心的项目减少了无保护性交，并增加了安全套的使用。然而，研究在人群、干预类型、对照组和结果测量方面存在异质性，因此计算汇总效应的荟萃分析是不合适的。尽管基于夫妇的艾滋病毒预防方法最初看起来很有希望，但还需要进行更多的研究，为基于夫妇的艾滋病毒预防建立更强有力的理论和方法基础，未来的干预措施必须更加关注同性恋夫妇、青少年和年轻人的关系。
HIV is frequently transmitted in the context of partners in a committed relationship, thus couples-focused HIV prevention interventions are a potentially promising modality for reducing infection. We conducted a systematic review of studies testing whether couples-focused behavioral prevention interventions reduce HIV transmission and risk behavior. We included studies using randomized controlled trial designs, quasi-randomized controlled trials and nonrandomized controlled studies. We searched five electronic databases and screened 7628 records. Six studies enrolling 1,084 couples met inclusion criteria and were included in this review. Results across studies consistently indicated that couples-focused programs reduced unprotected sexual intercourse and increased condom use compared with control groups. However, studies were heterogeneous in population, type of intervention, comparison groups, and outcomes measures, and so meta-analysis to calculate pooled effects was inappropriate. Although couples-based approaches to HIV prevention appear initially promising, additional research is necessary to build a stronger theoretical and methodological basis for couples-based HIV prevention, and future interventions must pay closer attention to homosexual couples, adolescents and young people in relationships.
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DOI：
10.1093/jurban/jti111
发表时间：
2005-09-01
影响因子：
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作者：
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影响因子：
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