Polyamines : a universal molecular nexus for growth, survival, and specialized metabolism
Polyamines : a universal molecular nexus for growth, survival, and specialized metabolism
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发表时间：
2015
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通讯作者：
T. Kusano;Hideyuki Suzuki
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作者：
T. Kusano;Hideyuki Suzuki
第一部分多胺的生物合成，- 1多胺在真核生物，细菌和细菌中的生物合成。2嗜热微生物中的长链和支链多胺3植物多胺生物合成的调控与多样性第二部分多胺的分解作用4原核生物中的多胺催化剂5哺乳动物多胺催化剂- 6植物中的多胺催化剂第三部分多胺稳巢作用- 7抗酶。8细菌抗酶。9植物中的多胺稳态：进化上保守的上游ORF的作用。第四部分多胺在生长中的作用10多胺亚精胺作为eIF 5A中羟腐胺赖氨酸修饰前体的作用。第11章多胺调制子：编码蛋白质的基因，其合成在翻译水平上被多胺增强。12嗜热菌中的蛋白质合成和多胺：多胺对核酸维持和基因表达的影响。第五部分多胺在生存中的作用植物逆境反应中的13种多胺第VI部多胺转运蛋白- 14细菌多胺转运系统的最新进展。植物中的15种多胺运输系统第VII部分多胺衍生的次级代谢物- 16植物中的多胺衍生生物碱：生物合成的分子阐明。来自蜘蛛和黄蜂的17种多胺毒素第八部分多胺对离子通道的作用18多胺阻断抑制整流钾（Kir）通道。多胺对植物离子通道和泵的作用20精胺和艾芬地尔对N-甲基-d-天冬氨酸受体的调节第九部分多胺和寿命21多胺和哺乳动物的长寿。22多胺与植物激素的相互作用：几个层次的串扰。第十部分诊断和药物靶点23人尿中的N1，N12-二乙酰精胺：作为肿瘤标志物的性能、定量、产生和排泄。24寄生原生动物中多胺生物合成途径的靶向研究。
PART I BIOSYNTHESIS OF POLYAMINES,- 1 Biosynthesis of Polyamines in Eukaryotes, Archaea, and Bacteria.- 2 Long-Chain and Branched Polyamines in Thermophilic Microbes.- 3 Regulation and Diversity of Polyamine Biosynthesis in Plants.- PART II CATABOLISM OF POLYAMINES.- 4 Polyamine Catabolism in Prokaryotes.- 5 Mammalian Polyamine Catabolism.- 6 Polyamine Catabolism in Plants.- PART III POLYAMINE HOMEOSTASIS.- 7 Antizyme.- 8 Bacterial Antizyme.- 9 Polyamine Homeostasis in Plants: The Role(s) of Evolutionarily Conserved Upstream ORFs.- PART IV ROLES OF POLYAMINES IN GROWTH.- 10 Role of the Polyamine Spermidine as a Precursor for Hypusine Modification in eIF5A.- 11 The Polyamine Modulon: Genes Encoding Proteins Whose Synthesis Is Enhanced by Polyamines at the Level of Translation.- 12 Protein Synthesis and Polyamines in Thermophiles: Effect of Polyamines on Nucleic Acid Maintenance and Gene Expression.- PART V ROLES OF POLYAMINES IN SURVIVAL.- 13 Polyamines in Plant Stress Response.- PART VI POLYAMINE TRANSPORTERS.- 14 Recent Advances in Bacterial Polyamine Transport Systems.- 15 Polyamine Transport Systems in Plants.- PART VII POLYAMINE-DERIVED SECONDARY METABOLITES.- 16 Polyamine-Derived Alkaloids in Plants: Molecular Elucidation of Biosynthesis.- 17 Polyamine Toxins from Spiders and Wasps.- PART VIII ACTION OF POLYAMINES ON ION CHANNELS.- 18 Polyamine Block of Inwardly Rectifying Potassium (Kir) Channels.- 19 Polyamine Action on Plant Ion Channels and Pumps.- 20 Regulation of N-Methyl-d-Aspartate Receptors by Spermine and Ifenprodil.- PART IX POLYAMINES AND LONGEVITY.- 21 Polyamines and Longevity in Mammals.- 22 Polyamine Interactions with Plant Hormones: Crosstalk at Several Levels.- PART X DIAGNOSIS AND DRUG TARGETS.- 23 N1, N12-Diacetylspermine in Human Urine: Performance as a Tumor Marker, Quantification, Production, and Excretion.- 24 Targeting the Polyamine Biosynthetic Pathway in Parasitic Protozoa.