Impact of the Human Genome Project on epidemiologic research.
Impact of the Human Genome Project on epidemiologic research.
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DOI：
10.1093/oxfordjournals.epirev.a017943
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发表时间：
1997
影响因子：
5.5
通讯作者：
D. Ellsworth;D. M. Hallman;E. Boerwinkle
中科院分区：
文献类型：
--
作者：
D. Ellsworth;D. M. Hallman;E. Boerwinkle
Traditionally, the fields of human genetics and epidemiology were independent disciplines with minimal interaction between them. Over the years, however, genetic concepts were slowly integrated with epidemiologic methods to capitalize on the advantages of thendiverse perspectives and expertise (1). By the late 1970s, genetic epidemiology emerged as a formal discipline and blossomed throughout the ensuing decades as advances in molecular biology advanced our understanding of human genetic disease (2-5). Genetic epidemiology relates genetic characteristics that may be influenced by environmental exposures to the distribution of disease among relatives and within diverse human populations. The primary objective of this field is to better understand the genetic etiology of disease in order to facilitate early prediction and design more effective intervention strategies.
