Are girls with ADHD at risk for eating disorders? Results from a controlled, five-year prospective study
Are girls with ADHD at risk for eating disorders? Results from a controlled, five-year prospective study
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DOI：
10.1097/dbp.0b013e3180327917
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发表时间：
2007-08-01
影响因子：
2.4
通讯作者：
Zeitlin, Sarah
中科院分区：
文献类型：
--
作者：
Biederman, Joseph;Ball, Sarah W.;Zeitlin, Sarah
目的：在大量患有和不患有注意力缺陷多动障碍（ADHD）的青少年女孩人群中，评价ADHD与进食障碍之间的相关性。方法：我们使用考克斯比例风险生存模型估计终生饮食失调（神经性厌食症或贪食症）的发病率。然后，对伴或不伴进食障碍的ADHD女孩进行了合并症、ADHD病程、生长和青春期的比较。结果：ADHD女孩在整个随访期间符合饮食失调标准的可能性是对照组女性的3.6倍。与没有进食障碍的ADHD女孩相比，患有进食障碍的女孩患重度抑郁症、焦虑症和破坏性行为障碍的比率明显更高。患有ADHD和饮食失调的女孩月经初潮的平均年龄明显早于其他ADHD女孩。在有和没有进食障碍的ADHD女孩之间没有检测到ADHD相关性的其他差异。结论：ADHD显著增加进食障碍的风险。患有ADHD的女孩中存在进食障碍增加了额外发病率和功能障碍的风险。
Objective: To evaluate the association between attention-deficit/hyperactivity disorder (ADHD) and eating disorders in a large adolescent population of girls with and without ADHD. Method: We estimated the incidence of lifetime eating disorders (either anorexia or bulimia nervosa) using Cox proportional hazard survival models. Comparisons between ADHD girls with and without eating disorders were then made on measures of comorbidity, course of ADHD, and growth and puberty. Results: ADHD girls were 3.6 times more likely to meet criteria for an eating disorder throughout the follow-up period compared to control females. Girls with eating disorders had significantly higher rates of major depression, anxiety disorders, and disruptive behavior disorder compared to ADHD girls without eating disorders. Girls with ADHD and eating disorders had a significantly earlier mean age at menarche than other ADHD girls. No other differences in correlates of ADHD were detected between ADHD girls with and without eating disorders. Conclusions: ADHD significantly increases the risk of eating disorders. The presence of an eating disorder in girls with ADHD heightens the risk of additional morbidity and dysfunction.