Optical coherence tomography angiography in glaucoma: a mini-review.
Optical coherence tomography angiography in glaucoma: a mini-review.
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DOI：
10.12688/f1000research.11691.1
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Leung CKS
中科院分区：
文献类型：
--
作者：
Wan KH;Leung CKS
光学相干断层扫描血管成像(OCT-A)的出现为以无创、无染料的方式显示视网膜血管提供了新的机会，有助于识别青光眼的血管异常。虽然许多研究表明OCT-A测量的青光眼患者的视网膜和视神经头部血管密度和血流指数降低，但与OCT测量相比，OCT-A是否为青光眼的检测和监测提供了额外的信息尚不清楚，如视网膜神经纤维层厚度、神经视网膜边缘宽度和神经节细胞内网状层厚度。需要进行纵向研究来阐明OCT-A检测到的血管异常是青光眼视神经损害的原因还是结果。
The advent of optical coherence tomography angiography (OCT-A) provides a new opportunity to visualize the retinal vasculature in a non-invasive and dye-free manner which may help identify vascular abnormalities in glaucoma. While a reduction in retinal and optic nerve head vessel densities and blood flow indexes measured by OCT-A has been demonstrated in patients with glaucoma in many studies, it is unclear whether OCT-A provides additional information for the detection and monitoring of glaucoma compared with OCT measurements such as retinal nerve fiber layer thickness, neuroretinal rim width, and ganglion cell inner plexiform layer thickness. Longitudinal studies are needed to elucidate whether vascular abnormalities detected by OCT-A are a cause or a consequence of optic nerve damage in glaucoma.