Effects of Action Observational Training Plus Brain-Computer Interface-Based Functional Electrical Stimulation on Paretic Arm Motor Recovery in Patient with Stroke: A Randomized Controlled Trial

Effects of Action Observational Training Plus Brain-Computer Interface-Based Functional Electrical Stimulation on Paretic Arm Motor Recovery in Patient with Stroke: A Randomized Controlled Trial
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DOI:
10.1002/oti.1403
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发表时间:
2016-03-01
影响因子:
1.5
通讯作者:
Lee, ByoungHee
Lee, ByoungHee
中科院分区:
医学4区
文献类型:
--
作者:
Kim, TaeHoon;Kim, SeongSik;Lee, ByoungHee

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本研究旨在探讨动作观察训练(AOT)联合基于脑-机接口的功能性电刺激(BCI-FES)对脑卒中偏瘫患者上肢运动功能恢复的影响。这是一项基于医院的随机对照试验,评估者为盲态。将30例首次卒中患者随机分为两组:BCI-FES组(n=15)和对照组(n=15)。BCI-FES组在常规治疗的基础上,给予AOT + BCI-FES治疗,每周5次,共4周。主要观察指标为Fugl-Meyer上肢功能评分、运动活动日志(MAL)、改良Barthel指数和瘫痪臂活动度,由盲法评估者分别于基线和4周进行评估。两组之间的所有基线结果均无显著差异。4周后,BCI-FES组Fugl-Meyer上肢功能评分(总评分、肩关节评分和腕关节评分)、MAL(使用活动度和运动质量)、改良Barthel指数和腕关节屈曲活动度评分均显著高于对照组(p
The purpose of this study was to investigate whether action observational training (AOT) plus brain-computer interface-based functional electrical stimulation (BCI-FES) has a positive influence on motor recovery of paretic upper extremity in patients with stroke. This was a hospital-based, randomized controlled trial with a blinded assessor. Thirty patients with a first-time stroke were randomly allocated to one of two groups: the BCI-FES group (n=15) and the control group (n=15). The BCI-FES group administered to AOT plus BCI-FES on the paretic upper extremity five times per week during 4weeks while both groups received conventional therapy. The primary outcomes were the Fugl-Meyer Assessment of the Upper Extremity, Motor Activity Log (MAL), Modified Barthel Index and range of motion of paretic arm. A blinded assessor evaluated the outcomes at baseline and 4weeks. All baseline outcomes did not differ significantly between the two groups. After 4weeks, the Fugl-Meyer Assessment of the Upper Extremity sub-items (total, shoulder and wrist), MAL (MAL-Activity of Use and Quality of Movement), Modified Barthel Index and wrist flexion range of motion were significantly higher in the BCI-FES group (p