Measurements of optic disk size with HRT II, stratus OCT, and funduscopy are not interchangeable
Measurements of optic disk size with HRT II, stratus OCT, and funduscopy are not interchangeable
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DOI：
10.1016/j.ajo.2006.03.065
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发表时间：
2006-09-01
影响因子：
4.2
通讯作者：
Ritch, Robert
中科院分区：
文献类型：
--
作者：
Barkana, Yaniv;Harizman, Noga;Ritch, Robert
中心点目的：评估裂隙灯眼底镜、光学相干断层扫描（OCT-3）和共焦扫描激光眼底镜（HRT-II）测量视盘大小的可行性practice.center。设计：前瞻性非随机临床研究。方法：用三种方法测量垂直椎间盘直径（VDD）。通过OCT和HRT打印机获得椎间盘面积。使用Bland-Altman图和95%一致性限（LoA）评估测量VDD的方法之间的真实一致性。statistics.center结果：48例患者入组（平均年龄53.4 ± 14.3岁）。眼底镜、HRT和OCT检查的VDD（平均值+/- SD）分别为1.58 +/- 0.15、1.70 +/- 0.22和1.90 +/- 0.24 mm。观察到非常大的LoA：OCT和HRT为-0.29至0.70 mm，OCT和眼底镜为-0.07至0.71 mm，HRT和眼底镜为-0.29至0.53 mm。无论是比较椎间盘直径还是面积，使用两种椎间盘定义，将椎间盘大小分类为小、平均或大的一致性较差（kappa < 0.4）。结论：我们观察到HRT、OCT和眼底镜在估计椎间盘大小方面存在很大差异。size.center这排除了在临床实践中这些测量值的可互换使用，并且不允许提出简单的转换公式。此外，这些方法在将椎间盘大小分类为小、平均或大方面的一致性较差。目前，对于每种测量方式，只能单独定义绝对和相对椎间盘大小的估计。
center dot PURPOSE: To assess the interchangeability of optic disk size measurements using slit-lamp funduscopy, optical coherence tomography (OCT-3), and confocal scanning laser ophthalmoscopy (HRT-II) in clinical practice.center dot DESIGN: Prospective nonrandomized clinical study. center dot METHODS: Measurements of vertical disk diameter (VDD) were obtained with the three methods. Disk area was obtained from OCT and HRT printouts. True agreement between methods in measuring VDD was assessed using Bland-Altman graphs and 95% limits of agreement (LoA). Disks were classified as small, average, or large, and agreement between methods in this classification was assessed using kappa statistics.center dot RESULTS: Forty-eight patients were enrolled (mean age 53.4 +/- 14.3 years). VDD (mean +/- SD) was 1.58 +/- 0.15, 1.70 +/- 0.22, and 1.90 +/- 0.24 mm with funduscopy, HRT, and OCT, respectively. Very large LoA were observed: -0.29 to 0.70 mm for OCT and HRT, -0.07 to 0.71 mm for OCT and funduscopy, and -0.29 to 0.53 mm for HRT and funduscopy. There was poor agreement (kappa < 0.4) in classification of disk size as small, average, or large whether disk diameter or area was compared and using two definitions of disk size.center dot CONCLUSIONS: We observed a large range of differences in estimating disk size with HRT, OCT, and funduscopy. This precludes interchangeable use of these measurements in clinical practice, and does not allow simple conversion formulas to be proposed. In addition, there is poor agreement between these methods in classifying disk size as small, average, or large. At present, estimation of both absolute and relative disk size can only be defined separately for each measurement modality.