Effect of age on mortality in coronary artery bypass surgery in New York, 1991-1992.
Effect of age on mortality in coronary artery bypass surgery in New York, 1991-1992.
复制标题
年龄对纽约冠状动脉搭桥手术死亡率的影响，1991-1992 年。
DOI：
10.1016/0002-8703(94)90750-1
复制
发表时间：
1994
影响因子：
4.8
通讯作者：
Burke,J
中科院分区：
文献类型：
--
作者：
Hannan,EL;Burke,J
本研究的目的是确定年龄对1991年和1992年在纽约接受冠状动脉旁路移植术（CABG）手术的所有30，972例患者的住院死亡率的影响。40-49岁、50-59岁、60-64岁、65-69岁和70-74岁患者的死亡率相对较低（分别为1.10%、1.65%、2.17%、2.76%和3.36%）。年龄在75 ~ 79岁（5.28%）和≥80岁（8.31%）的患者手术死亡率迅速上升。在考虑了其他重要危险因素的影响后，为了检验年龄对死亡率的独立影响，建立了一个多变量统计模型，以确定死亡率的重要独立预测因素。年龄是24个重要预测因素之一，年龄≥75岁的死亡风险比年龄较小的死亡风险高得多。例如，假设所有其他重要风险因素相同，80岁患者在医院死亡的几率是50岁患者在医院死亡的几率的3.25倍。
The purpose of this study was to determine the effect of age on the in-hospital mortality of all 30,972 patients undergoing coronary artery bypass graft (CABG) surgery in New York in 1991 and 1992. Mortality rates were relatively low for patients 40–49, 50–59, and 60–64, 65–69, and 70–74 years old (1.10%, 1.65%, 2.17%, 2.76%, and 3.36%, respectively). However, CABG surgery mortality increased rapidly for patients 75 to 79 years old (5.28%) and patients ≥80 years old (8.31%). To examine the independent effect of age on mortality after accounting for the effects of other significant risk factors, a multivariate statistical model was developed to identify the significant independent predictors of mortality. Age emerged as 1 of 24 significant predictors, with age ≥75 demonstrating much higher mortality risk than lesser age. For example, the odds of an 80-year-old patient's dying in the hospital were 3.25 times the odds of a 50-year-old patient's dying in the hospital, assuming all other significant risk factors were identical.