Threshold depolarization measurements in resting human motoneurones

Threshold depolarization measurements in resting human motoneurones
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静息人类运动神经元的阈值去极化测量

DOI:
10.1016/0165-0270(91)90097-j
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发表时间:
1991
影响因子:
3
通讯作者:
T. Miles
T. Miles
中科院分区:
医学4区
文献类型:
--
作者:
K. Türker;T. Miles

文献摘要

被引文献

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阈值去极化被定义为刚好使神经元达到其放电阈值的去极化幅度。在这里,描述了一种新的技术,用于测量阈值去极化在休息的人运动神经元。刺激胫神经的强度刚好足以产生la传入齐射,以激活比目鱼肌中的单个运动单元。然后通过自主激活来募集相同的运动单位,并且通过先前描述的方式来确定由该刺激引起的EPSP的幅度。对于成功测试的所有6个运动神经元,阈值去极化的值约为5 mV。
Threshold depolarization is defined as the amplitude of the depolarization that will just bring a neurone to its firing threshold. Here, a novel technique is described for the measurement of threshold depolarization in resting human motoneurones. The tibial nerve was stimulated at an intensity that was just sufficient for the resulting la afferent volley to activate a single motor unit in the soleus muscle. The same motor unit was then recruited by voluntary activation, and the amplitude of the EPSP elicited by this stimulus was determined by a manner described earlier. The value found for the threshold depolarization was around 5 mV for all 6 motoneurones that were successfully tested.