Rapid carbonylative coupling reactions using palladium(I) dimers: applications to 11CO-radiolabelling for the synthesis of PET tracers
Rapid carbonylative coupling reactions using palladium(I) dimers: applications to 11CO-radiolabelling for the synthesis of PET tracers
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DOI：
10.1039/c1ob05268c
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发表时间：
2011-01-01
影响因子：
3.2
通讯作者：
Vilar, Ramon
中科院分区：
文献类型：
--
作者：
Buscemi, Gabriella;Miller, Philip W.;Vilar, Ramon
具有空间位阻膦的钯二聚物已被证明是用于芳基卤化物的氨基羰基化以产生酰胺的优异的预催化剂，并且其中之一已成功地用作合成用于PET成像的C-11-放射性标记的酰胺的预催化剂。
Palladium dimers with sterically hindered phosphines have been shown to be excellent pre-catalysts for the aminocarbonylation of aryl halides to yield amides and one of them has been successfully employed as a pre-catalyst for the synthesis of C-11-radiolabelled amides for PET imaging.