Mandarin fish (Sinipercidae) genomes provide insights into innate predatory feeding
Mandarin fish (Sinipercidae) genomes provide insights into innate predatory feeding
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鳜鱼（鳜科）基因组提供了对先天掠食性进食的见解
DOI：
10.1038/s42003-020-1094-y
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发表时间：
2020-07-09
影响因子：
5.9
通讯作者：
Liang, Xu-Fang
中科院分区：
文献类型：
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作者：
He, Shan;Li, Ling;Liang, Xu-Fang
鳜鱼（鳜科）是食鱼动物，仅以活鱼苗为食。与高等脊椎动物不同，硬骨鱼的摄食行为主要由遗传反应驱动，没有通过向父母学习而改变。鳜鱼可以作为研究摄食行为的优秀模式生物。我们报告了鳜的长读长、染色体规模的基因组组装以及克氏鳜、鳜和白头鳜的基因组组装。正选择分析揭示了与捕食/攻击、生长、幽门盲肠和广盐性相关的基因的快速适应性进化。鳜鱼身上很少有鳃耙。类似地，我们发现缺乏 inedar 的斑马鱼具有鳃耙丢失表型和更具捕食性的习性，浮游动物的摄入量减少，但猎物鱼的摄入量增加。 bmp4的较高表达可以通过结合edar上游的Xvent-1位点抑制dar表达和鳃耙发育，可能导致鳜鱼的捕食性摄食。
Mandarin fishes (Sinipercidae) are piscivores that feed solely on live fry. Unlike higher vertebrates, teleosts exhibit feeding behavior driven mainly by genetic responses, with no modification by learning from parents. Mandarin fishes could serve as excellent model organisms for studying feeding behavior. We report a long-read, chromosomal-scale genome assembly forSiniperca chuatsiand genome assemblies forSiniperca kneri,Siniperca scherzeriandCoreoperca whiteheadi. Positive selection analysis revealed rapid adaptive evolution of genes related to predatory feeding/aggression, growth, pyloric caeca and euryhalinity. Very few gill rakers are observed in mandarin fishes; analogously, we found that zebrafish deficient inedarhad a gill raker loss phenotype and a more predatory habit, with reduced intake of zooplankton but increased intake of prey fish. Higher expression ofbmp4, which could inhibitedarexpression and gill raker development through binding of a Xvent-1 site upstream ofedar, may cause predatory feeding inSiniperca.