Histocompatibility and other risk factors for histological rejection of human cardiac allografts during the first three months following transplantation.
Histocompatibility and other risk factors for histological rejection of human cardiac allografts during the first three months following transplantation.
复制标题
移植后头三个月内人心脏同种异体移植物组织相容性和其他危险因素。
DOI：
10.1097/00007890-199109000-00019
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发表时间：
1991
期刊：
影响因子：
6.2
通讯作者：
Duquesnoy,RJ
中科院分区：
文献类型：
--
作者：
Zerbe,TR;Arena,VC;Kormos,RL;Griffith,BP;Hardesty,RL;Duquesnoy,RJ
A histological analysis of 2564 endomyocardial biopsies was conducted in 349 cardiac transplant patients to determine potential risk factors for acute cellular rejection during the first three months following transplantation. This analysis dealt with the frequency, time of onset, and duration of cellular rejection. Patients on perioperative RATG experienced significantly less rejection than patients on OKT3 or without antilymphocyte antibody immunoprophylaxis. A trend was noted toward increased rejection in recipients diagnosed originally with chronic myocarditis compared with patients in other disease categories including ischemic heart disease and dilated cardiomyopathy. No significant differences were seen in histological rejection between male and female recipients. On the other hand, patients over 55 years of age were found at lower risk of histological rejection.
