New Light on Disordered Ensembles: Ab Initio Structure Determination of One Particle from Scattering Fluctuations of Many Copies

New Light on Disordered Ensembles: Ab Initio Structure Determination of One Particle from Scattering Fluctuations of Many Copies
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DOI:
10.1103/physrevlett.106.115501
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发表时间:
2011-03-14
影响因子:
8.6
通讯作者:
Spence, J. C. H.
Spence, J. C. H.
中科院分区:
物理与天体物理1区
文献类型:
--
作者:
Saldin, D. K.;Poon, H. C.;Spence, J. C. H.

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我们报告的第一个实验从头计算重建的单个粒子的图像从波动的散射从合奏的副本,随机取向的轴。该方法适用于在空间或时间中冻结的相同粒子(如通过X射线自由电子激光的快照衍射)。这些波动增强了可从诸如常规小角度X射线散射的实验获得的信息。
We report on the first experimental ab initio reconstruction of an image of a single particle from fluctuations in the scattering from an ensemble of copies, randomly oriented about an axis. The method is applicable to identical particles frozen in space or time (as by snapshot diffraction from an x-ray free electron laser). These fluctuations enhance information obtainable from an experiment such as conventional small angle x-ray scattering.