The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001-2011.
The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001-2011.
复制标题
世贸中心暴露对纽约市消防员慢性鼻窦炎诊断潜伏期的影响：2001-2011 年。
DOI：
10.1136/oemed-2015-103094
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发表时间：
2016
影响因子：
4.9
通讯作者：
Prezant,David
中科院分区：
文献类型：
--
作者：
Weakley,Jessica;Hall,CharlesB;Liu,Xiaoxue;Zeig-Owens,Rachel;Webber,MayrisP;Schwartz,Theresa;Prezant,David
目的评估9/11袭击后10年内，世界贸易中心（WTC）暴露对医生诊断的消防员慢性鼻窦炎（CRS）的影响（2001年9月11日至2011年9月10日）方法我们研究了在9/10袭击后的十年中，消防员中WTC暴露与医生诊断的CRS发生率之间关系的时间效应。11（2001年9月11日至2011年9月10日）。暴露按到达世贸中心地点的时间分组如下：（高）2001年9月11日上午（n=1623）;（中等）2001年9月11日或2001年9月12日下午（n=7025）;或（低）2001年9月13-24日（n=1200）。分段指数生存模型被用来估计发病率的曝光组，与最大似然估计的相对发病率的变化点。ResultsIncidences显着增加后，2007年由于一个程序的变化，提供免费的医疗，但在所有曝光组的增加是相似的。因此，我们在研究期间未观察到变化点，这意味着CRS疾病暴露组（高vs中vs低）的相对发生率在研究期间未发生显著变化。CRS发展的相对率为1.99（95%CI =1.64至2.41）高与低曝光，和1.52（95%CI =1.28至1.80）中与低曝光在10年的后续period.ConclusionsThe风险CRS在FDNY消防员出现WTC曝光增加，并没有减少自曝光的时间。
ObjectiveTo assess how the effect of World Trade Center (WTC) exposure on physician-diagnosed chronic rhinosinusitis (CRS) in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011).MethodsWe examined temporal effects on the relation between WTC exposure and the incidence of physician diagnosed CRS in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011). Exposure was grouped by time of arrival at the WTC site as follows: (high) morning 11 September 2001 (n=1623); (moderate) afternoon 11 September 2001 or 12 September 2001 (n=7025); or (low) 13–24 September 2001 (n=1200). Piecewise exponential survival models were used to estimate incidences by exposure group, with change points in the relative incidences estimated by maximum likelihood.ResultsIncidences dramatically increased after 2007 due to a programmatic change that provided free medical treatment, but increases were similar in all exposure groups. For this reason, we observed no change point during the study period, meaning the relative incidence by exposure group (high vs moderate vs low) of CRS disease did not significantly change over the study period. The relative rate of developing CRS was 1.99 (95% CI=1.64 to 2.41) for high versus low exposure, and 1.52 (95% CI=1.28 to 1.80) for moderate versus low exposure during the 10-year follow-up period.ConclusionsThe risk of CRS in FDNY firefighters appears increased with WTC-exposure, and has not diminished by time since exposure.