DEMONSTRATION THAT BONE-MINERAL DENSITY OF THE LUMBAR SPINE, TROCHANTER, AND FEMORAL-NECK IS HIGHER IN BLACK THAN IN WHITE YOUNG MEN
DEMONSTRATION THAT BONE-MINERAL DENSITY OF THE LUMBAR SPINE, TROCHANTER, AND FEMORAL-NECK IS HIGHER IN BLACK THAN IN WHITE YOUNG MEN
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DOI：
10.1007/bf00298737
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发表时间：
1995-01-01
影响因子：
4.2
通讯作者：
SHARY, JR
中科院分区：
文献类型：
--
作者：
BELL, NH;GORDON, L;SHARY, JR
黑人的骨质疏松症和髋部和脊柱骨折的发生率低于白人。为了确定黑人男性的骨量是否增加，并评估体重和年龄的影响，用双光子吸收法测量了59名正常白人男性和40名20-50岁的黑人男性腰椎、粗隆和股骨颈的骨密度(BMD)。两组患者的体重和年龄差异无统计学意义。采用单光子骨密度仪测定患者的中段骨密度。采用多元回归方法进行各组间的独立分析和两组间的共同分析。在调整体重后，黑人和白人的年龄与股骨颈的BMD以及黑人的粗隆骨密度呈负相关。当体重独立于年龄进行分析时，它是黑人男性中段和白人男性股骨颈骨密度的积极预测因子。尽管年龄和体重在BMD上存在种族差异，但当黑人和白人男性的数据结合在一起时，种族和年龄或种族和体重之间没有显著的交互作用。种族对腰椎、粗隆和股骨颈中段的骨密度有非常显著的影响，在这些部位，黑人的骨密度高于白人。随着年龄的增长，股骨中段和股骨颈的骨密度显著下降，而粗隆和股骨颈的骨密度随着体重的增加而显著增加。因此，黑人的骨量高于白人，骨量的差异可能是黑人骨质疏松症和骨折发生率较低的原因之一。
The incidence of osteoporosis and fractures of the hip and spine is lower in black than in white subjects. To determine whether bone mass is increased in black men and to assess the influence of body weight and age, bone mineral density (BMD) of the lumbar spine, trochanter, and femoral neck was measured by dual-photon absorptiometry in 59 normal white men and 40 black men between the ages of 20 and 50 years. Body weight and age were not different from each other in the two groups. BMD of the midradius was measured by single-photon absorptiometry. Multivariate regression was used for independent analysis of each group and for analysis of the two groups together. After adjusting for body weight, age was inversely related to BMD of the femoral neck in both blacks and whites and of the trochanter in blacks. When body weight was analyzed independently of age, it was a positive predictor for BMD of the midradius of black men and of the femoral neck in white men. Despite the racial differences in age and weight on BMD, there were no significant interactions between race and age or race and weight when the data from black and white men were combined. Race had a highly significant effect on BMD of the lumbar spine, trochanter, and femoral neck midradius, and BMD was higher in blacks than in whites at these sites. There were significant declines in BMD with age at the midradius and femoral neck and significant increases in BMD with body weight at the trochanter and femoral neck. Thus, bone mass is higher in black than in white men and the difference in bone mass may contribute to the lower incidence of osteoporosis and fractures in blacks.