CONCENTRATIONS OF 3 HAPTEN-BINDING IMMUNOGLOBULINS IN POOLED NORMAL HUMAN-SERUM
CONCENTRATIONS OF 3 HAPTEN-BINDING IMMUNOGLOBULINS IN POOLED NORMAL HUMAN-SERUM
复制标题
DOI：
10.1002/eji.1830060204
复制
发表时间：
1976-01-01
影响因子：
5.4
通讯作者：
MAKELA, O
中科院分区：
文献类型：
--
作者：
KARJALAINEN, K;MAKELA, O
通过使用免疫吸附剂和半抗原洗脱来测量人IgM中天然抗DNP-cap、抗NIP-cap或抗阿坝-TYR的量。我们发现，1.0%的合并人IgM对DNP-cap具有特异性，0.2%对NIP-cap具有特异性，0.02%对阿坝-TYR具有特异性。发现半抗原NIP和DNP在用天然抗体检测时具有交叉反应性，即使它们在用免疫抗体检测时不具有交叉反应性。
The amount of natural anti‐DNP‐cap, anti‐NIP‐cap or anti‐ABA‐TYR in human IgM was measured by using immunoabsorbents and hapten elution. We found that 1.0 % of pooled human IgM is specific for DNP‐cap, 0.2 % for NIP‐cap and 0.02 % for ABA‐TYR. Haptens NIP and DNP were found to be cross‐reactive when tested with natural antibodies even though they were not cross‐reactive when tested with immune antibodies.