Successful switching of anticoagulants in a patient with superficial siderosis and atrial fibrillation
Successful switching of anticoagulants in a patient with superficial siderosis and atrial fibrillation
复制标题
浅表铁质沉着症合并心房颤动患者成功更换抗凝药物
DOI：
10.1111/ncn3.12094
复制
发表时间：
2016
影响因子：
0.4
通讯作者：
ANdo Y
中科院分区：
文献类型：
--
作者：
Inatomi Y;Nakajima;M;Yonehara T;ANdo Y
一例78岁心房颤动患者接受华法林治疗后出现急性头痛、耳聋、小脑性共济失调和排尿困难。脑显像诊断为浅表性铁沉着；但未发现出血源。停用华法林后，他的神经功能缺损和脑脊液血减少了。阿哌沙班在发病2个月后开始使用，在转换这些抗凝药物18个月后，他的缺陷和铁沉着没有复发。
A 78‐year‐old man with atrial fibrillation treated with warfarin experienced acute headache, deafness, cerebellar ataxia and dysuria. Superficial siderosis was diagnosed on brain imaging; however, no bleeding sources were detected. His neurological deficits and bloody cerebrospinal fluid diminished after withdrawal of warfarin. Apixaban was started 2 months after the onset, and his deficits and siderosis had not recurred 18 months after switching these anticoagulants.