Characterization of reperfused infarcted myocardium from high-frequency intracardiac ultrasound imaging using homodyned K distribution
Characterization of reperfused infarcted myocardium from high-frequency intracardiac ultrasound imaging using homodyned K distribution
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DOI：
10.1109/tuffc.2002.1049735
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发表时间：
2002-11-01
影响因子：
3.6
通讯作者：
Greenleaf, JF
中科院分区：
文献类型：
--
作者：
Hao, XH;Bruce, CJ;Greenleaf, JF
梗死/再灌注引起的心肌变化（收缩带坏死、出血、水肿等）可能导致散射体密度增加和散射体排列的变化。这PAC每，为第一次，模型的散射条件下产生的超声和正常/再灌注梗死心肌的相互作用，使用homodyned K分布。此外，该方法被用来表征散射体密度的变化，通过计算每个分辨率单元的有效散射体数。讨论了衰减和扫描变换对有效散射元数估计的影响及可靠性。我们使用了在体内的数据采集使用高频心内超声成像（8.5 MHz）从左，右心室的开胸猪在急性梗死/再灌注模型。结果表明，零拍K分布描述了正常和异常心肌背向散射信号的统计分布。再灌注后梗死区散射体密度显著增加，与基线相同区域（闭塞前正常心肌）相比。再灌注后正常区域的散射体密度无明显变化。我们的结论是，homodyned K分布可以表征正常和再灌注梗死心肌使用高频心内超声图像。
Myocardial changes caused by infarction/reperfusion (contraction band necrosis, hemorrhage, edema, etc.) may result in an increased scatterer density and a variation in scatterer arrangement. This pac per, for the first time, models most of the scattering conditions resulting from the interaction of ultrasound and normal/reperfused infarcted myocardium using the homodyned K distribution. Furthermore, this method is used to characterize the change in scatterer density by calculating the effective scatterer number per resolution cell. The reliability and the effects of attenuation and scan conversion on effective scatterer number estimation are discussed. We used in vivo data acquired using high-frequency intracardiac ultrasound imaging (8.5 MHz) from the left and right ventricles of open-chest pigs in an acute infarction/reperfusion model. The results show that the homodyned K distribution describes the statistical distribution of backscattered signal from both normal and abnormal myocardium. A significant increase in scatterer density occurs in the infarcted region after reperfusion compared with the same region at baseline (normal myocardium prior to occlusion). The scatterer density of the normal region does not change significantly after reperfusion. We conclude that the homodyned K distribution may characterize normal and reperfused infarcted myocardium using high-frequency intracardiac ultrasound images.